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| {{enzyme
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| | Name = trimethylamine dehydrogenase
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| | EC_number = 1.5.8.2
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| | CAS_number = 39307-09-0
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| | IUBMB_EC_number = 1/5/8/2
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| | GO_code = 0050470
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| In [[enzymology]], a '''trimethylamine dehydrogenase''' ({{EC number|1.5.8.2}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
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| :trimethylamine + H<sub>2</sub>O + electron-transferring flavoprotein <math>\rightleftharpoons</math> dimethylamine + formaldehyde + reduced electron-transferring flavoprotein | |
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| The 3 [[substrate (biochemistry)|substrates]] of this enzyme are [[trimethylamine]], [[water|H<sub>2</sub>O]], and [[electron-transferring flavoprotein]], whereas its 3 [[product (chemistry)|products]] are [[dimethylamine]], [[formaldehyde]], and [[reduced electron-transferring flavoprotein]].
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| This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the CH-NH group of donors with a flavin as acceptor. The systematic name of this enzyme class is '''trimethylamine:electron-transferring flavoprotein oxidoreductase (demethylating)'''. This enzyme participates in [[methane metabolism]].
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| ==References==
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| {{reflist|1}}
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| * {{cite journal | author = Colby J and Zatman LJ | year = 1971 | title = The purification and properties of a bacterial trimethylamine dehydrogenase | journal = Biochem. J. | volume = 121 | issue = 1 | pages = 9 | pmid=5116569 | pmc = 1176516}}
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| * {{cite journal | author = Steenkamp DJ, Singer TP | year = 1978 | title = Participation of the iron-sulphur cluster and of the covalently bound coenzyme of trimethylamine dehydrogenase in catalysis | journal = Biochem. J. | volume = 169 | pages = 361–9 | pmid = 204297 | issue = 2 | pmc = 1184175 }}
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| * {{cite journal | author = Huang L, Rohlfs RJ, Hille R | year = 1995 | title = The reaction of trimethylamine dehydrogenase with electron transferring flavoprotein | journal = J. Biol. Chem. | volume = 270 | pages = 23958–65 | pmid = 7592591 | doi = 10.1074/jbc.270.41.23958 | issue = 41 }}
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| * {{cite journal | author = MJ, Scrutton NS | year = 2002 | title = Electron transfer and conformational change in complexes of trimethylamine dehydrogenase and electron transferring flavoprotein | journal = J. Biol. Chem. | volume = 277 | pages = 8457–65 | pmid = 11756429 | doi = 10.1074/jbc.M111105200 | last2 = Talfournier | first2 = F | last3 = Bobrov | first3 = A | last4 = Grossmann | first4 = JG | last5 = Vekshin | first5 = N | last6 = Sutcliffe | first6 = MJ | last7 = Scrutton | first7 = NS | issue = 10 }}
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| * {{cite journal | author = Scrutton NS, Sutcliffe MJ | year = 2000 | title = Trimethylamine dehydrogenase and electron transferring flavoprotein | journal = Subcell. Biochem. | volume = 35 | pages = 145–81 | pmid = 11192721 | doi = 10.1007/0-306-46828-X_5 }}
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| [[Category:EC 1.5.8]]
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| [[Category:Enzymes of unknown structure]]
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| {{1.5-enzyme-stub}}
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Greetings. Permit me start by telling you the author's title - Lili. Fixing puzzles is what she loves performing. For a even though she's been in Virginia. Generation and organizing has been her occupation for some time and her salary has been truly fulfilling. Check out out the most recent information on her internet site: http://www.valdepalacios.es/09_varios/contacto.html
my web blog; Zapatillas Nike