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| | Rusty Howie is the identify he enjoys to be referred to as with and he absolutely loves this name. Years ago he moved to Puerto Rico and his [https://www.gov.uk/search?q=relatives relatives] enjoys it. In his qualified lifetime he is a debt collector. Participating in [http://Www.bbc.co.uk/search/?q=lacross lacross] is the only interest his spouse would not approve of. You can always obtain his internet site in this article: http://www.portalalicante.com/nikeairmax/nikeairmaxhistory.asp<br><br> |
| {{enzyme
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| | Name = Linoleate diol synthase
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| | EC_number = 1.13.11.44
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| | CAS_number =
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| | IUBMB_EC_number = 1/13/11/44
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| | GO_code =
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| In [[enzymology]], a '''linoleate diol synthase''' ({{EC number|1.13.11.44}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
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| :linoleate + O<sub>2</sub> <math>\rightleftharpoons</math> (9Z,12Z)-(7S,8S)-dihydroxyoctadeca-9,12-dienoate | | my web page: [http://www.portalalicante.com/nikeairmax/nikeairmaxhistory.asp Nike air max History] |
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| Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[linoleate]] and [[oxygen|O<sub>2</sub>]], whereas its [[product (chemistry)|product]] is [[(9Z,12Z)-(7S,8S)-dihydroxyoctadeca-9,12-dienoate]].
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| This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on single donors with O<sub>2</sub> as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O<sub>2</sub>. The systematic name of this enzyme class is '''linoleate:oxygen 7S,8S-oxidoreductase'''. This enzyme is also called '''linoleate (8R)-dioxygenase'''. This enzyme participates in [[linoleic acid metabolism]].
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| ==References==
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| {{reflist|1}}
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| * {{cite journal | author = Brodowsky ID, Hamberg M, Oliw EH | date = 1992 | title = A linoleic acid (8R)-dioxygenase and hydroperoxide isomerase of the fungus Gaeumannomyces graminis. Biosynthesis of (8R)-hydroxylinoleic acid and (7S,8S)-dihydroxylinoleic acid from (8R)-hydroperoxylinoleic acid | journal = J. Biol. Chem. | volume = 267 | pages = 14738–45 | pmid = 1634517 | issue = 21 }}
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| * {{cite journal | author = Hamberg M, Zhang LY, Brodowsky ID, Oliw EH | date = 1994 | title = Sequential oxygenation of linoleic acid in the fungus Gaeumannomyces graminis: stereochemistry of dioxygenase and hydroperoxide isomerase reactions | journal = Arch. Biochem. Biophys. | volume = 309 | pages = 77–80 | pmid = 8117115 | doi = 10.1006/abbi.1994.1087 | issue = 1 }}
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| * {{cite journal | author = EH | date = 1999 | title = Cloning of linoleate diol synthase reveals homology with prostaglandin H synthases | journal = J. Biol. Chem. | volume = 274 | pages = 28219–24 | pmid = 10497176 | doi = 10.1074/jbc.274.40.28219 | last2 = Su | first2 = C | last3 = Osbourn | first3 = AE | last4 = Garosi | first4 = P | last5 = Hellman | first5 = U | last6 = Wernstedt | first6 = C | last7 = Oliw | first7 = EH | issue = 40 }}
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| * {{cite journal | author = Oliw EH, Su C, Skogstrom T, Benthin G | date = 1998 | title = Analysis of novel hydroperoxides and other metabolites of oleic, linoleic, and linolenic acids by liquid chromatography-mass spectrometry with ion trap MSn | journal = Lipids. | volume = 33 | pages = 843–52 | pmid = 9778131 | doi = 10.1007/s11745-998-0280-0 | issue = 9 }}
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| * {{cite journal | author = Su C, Oliw EH | date = 1996 | title = Purification and characterization of linoleate 8-dioxygenase from the fungus Gaeumannomyces graminis as a novel hemoprotein | journal = J. Biol. Chem. | volume = 271 | pages = 14112–8 | pmid = 8662736 | doi = 10.1074/jbc.271.24.14112 | issue = 24 }}
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| * {{cite journal | author = Su C, Sahlin M, Oliw EH | date = 1998 | title = A protein radical and ferryl intermediates are generated by linoleate diol synthase, a ferric hemeprotein with dioxygenase and hydroperoxide isomerase activities | journal = J. Biol. Chem. | volume = 273 | pages = 20744–51 | pmid = 9694817 | doi = 10.1074/jbc.273.33.20744 | issue = 33 }}
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| {{1.13-enzyme-stub}}
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| [[Category:EC 1.13.11]]
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| [[Category:Enzymes of unknown structure]]
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