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| {{enzyme
| | The name of the author is Jayson. For many years she's been working as a journey agent. My wife and I reside in Mississippi but now I'm considering other choices. To climb is some thing I truly appreciate doing.<br><br>my weblog; [http://myoceancounty.net/groups/apply-these-guidelines-when-gardening-and-grow/ psychic chat online] |
| | Name = 2-chlorobenzoate 1,2-dioxygenase
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| | EC_number = 1.14.12.13
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| | CAS_number = 125268-83-9
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| | IUBMB_EC_number = 1/14/12/13
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| | GO_code = 0018626
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| In [[enzymology]], a '''2-chlorobenzoate 1,2-dioxygenase''' ({{EC number|1.14.12.13}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
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| :2-chlorobenzoate + NADH + H<sup>+</sup> + O<sub>2</sub> <math>\rightleftharpoons</math> catechol + chloride + NAD<sup>+</sup> + CO<sub>2</sub>
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| The 4 [[substrate (biochemistry)|substrates]] of this enzyme are [[2-chlorobenzoate]], [[nicotinamide adenine dinucleotide|NADH]], [[hydrogen ion|H<sup>+</sup>]], and [[oxygen|O<sub>2</sub>]], whereas its 4 [[product (chemistry)|products]] are [[catechol]], [[chloride]], [[nicotinamide adenine dinucleotide|NAD<sup>+</sup>]], and [[carbon dioxide|CO<sub>2</sub>]].
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| This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of two atoms o oxygen into the other donor. The systematic name of this enzyme class is '''2-chlorobenzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, dechlorinating, decarboxylating)'''. This enzyme is also called '''2-halobenzoate 1,2-dioxygenase'''. This enzyme participates in [[benzoate degradation via coa ligation]]. It employs one [[cofactor (biochemistry)|cofactor]], [[iron]].
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| ==References==
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| {{reflist|1}}
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| * {{cite journal | doi = 10.1515/bchm3.1989.370.2.1173 | author = Fetzner S, Muller R, Lingens F | year = 1989 | title = Degradation of 2-chlorobenzoate by Pseudomonas cepacia 2CBS | journal = Biol. Chem. Hoppe-Seyler | volume = 370 | pages = 1173–82 | pmid = 2610934 | issue = 11 }}
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| [[Category:EC 1.14.12]]
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| [[Category:NADPH-dependent enzymes]]
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| [[Category:NADH-dependent enzymes]]
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| [[Category:Iron enzymes]]
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| [[Category:Enzymes of unknown structure]]
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| {{1.14-enzyme-stub}}
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The name of the author is Jayson. For many years she's been working as a journey agent. My wife and I reside in Mississippi but now I'm considering other choices. To climb is some thing I truly appreciate doing.
my weblog; psychic chat online