Leucyltransferase: Difference between revisions

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{{enzyme
| Name = mycocerosate synthase
| EC_number = 2.3.1.111
| CAS_number = 95229-19-9
| IUBMB_EC_number = 2/3/1/111
| GO_code = 0050111
| image =
| width =
| caption =
}}
In [[enzymology]], a '''mycocerosate synthase''' ({{EC number|2.3.1.111}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]


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:acyl-CoA + n methylmalonyl-CoA + 2n NADPH + 2n H<sup>+</sup> <math>\rightleftharpoons</math> multi-methyl-branched acyl-CoA + n CoA + n CO<sub>2</sub> + 2n NADP<sup>+</sup>
 
The 4 [[substrate (biochemistry)|substrates]] of this enzyme are [[acyl-CoA]], [[methylmalonyl-CoA]], [[nicotinamide adenine dinucleotide phosphate|NADPH]], and [[hydrogen ion|H<sup>+</sup>]], whereas its 4 [[product (chemistry)|products]] are [[multi-methyl-branched acyl-CoA]], [[coenzyme A|CoA]], [[carbon dioxide|CO<sub>2</sub>]], and [[nicotinamide adenine dinucleotide phosphate|NADP<sup>+</sup>]].
 
This enzyme belongs to the family of [[transferase]]s, specifically those [[acyltransferase]]s transferring groups other than aminoacyl groups. The systematic name of this enzyme class is '''acyl-CoA:methylmalonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing)'''. This enzyme is also called '''mycocerosic acid synthase'''.
 
==References==
{{reflist|1}}
* {{cite journal | author = Rainwater DL, Kolattukudy PE | date = 1985 | title = Fatty acid biosynthesis in Mycobacterium tuberculosis var. bovis Bacillus Calmette-Guerin. Purification and characterization of a novel fatty acid synthase, mycocerosic acid synthase, which elongates n-fatty acyl-CoA with methylmalonyl-CoA | journal = J. Biol. Chem. | volume = 260 | pages = 616&ndash;23  | pmid = 3880746 | issue = 1 }}
 
{{transferase-stub}}
 
[[Category:EC 2.3.1]]
[[Category:NADPH-dependent enzymes]]
[[Category:Enzymes of unknown structure]]

Latest revision as of 22:47, 17 March 2013

Template:Enzyme In enzymology, a mycocerosate synthase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

acyl-CoA + n methylmalonyl-CoA + 2n NADPH + 2n H+ multi-methyl-branched acyl-CoA + n CoA + n CO2 + 2n NADP+

The 4 substrates of this enzyme are acyl-CoA, methylmalonyl-CoA, NADPH, and H+, whereas its 4 products are multi-methyl-branched acyl-CoA, CoA, CO2, and NADP+.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-CoA:methylmalonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing). This enzyme is also called mycocerosic acid synthase.

References

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