Penicillin amidase: Difference between revisions

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{{enzyme
| Name = protein-glutamine glutaminase
| EC_number = 3.5.1.44
| CAS_number = 62213-11-0
| IUBMB_EC_number = 3/5/1/44
| GO_code = 0050568
| image =  
| width =  
| caption =  
}}
In [[enzymology]], a '''protein-glutamine glutaminase''' ({{EC number|3.5.1.44}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:protein L-glutamine + H<sub>2</sub>O <math>\rightleftharpoons</math> protein L-glutamate + NH<sub>3</sub>
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[protein L-glutamine]] and [[water|H<sub>2</sub>O]], whereas its two [[product (chemistry)|products]] are [[protein L-glutamate]] and [[ammonia|NH<sub>3</sub>]].
 
This enzyme belongs to the family of [[hydrolase]]s, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is '''protein-L-glutamine amidohydrolase'''. Other names in common use include '''peptidoglutaminase II''', '''glutaminyl-peptide glutaminase''', '''destabilase''', and '''peptidylglutaminase II'''.
 
==References==
{{reflist|1}}
* {{cite journal | author = Kikuchi M, Hayashida H, Nakano E, Sakaguchi K | date = 1971 | title = Peptidoglutaminase. Enzymes for selective deamidation of gamma-amide of peptide-bound glutamine | journal = Biochemistry. | volume = 10 | pages = 1222&ndash;9  | pmid = 4928623 | doi = 10.1021/bi00783a019 | issue = 7 }}
 
{{hydrolase-stub}}
 
[[Category:Hydrolases acting on nonpeptide C-N bonds]]
[[Category:Enzymes of unknown structure]]

Revision as of 16:49, 13 May 2013

Template:Enzyme In enzymology, a protein-glutamine glutaminase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

protein L-glutamine + H2O protein L-glutamate + NH3

Thus, the two substrates of this enzyme are protein L-glutamine and H2O, whereas its two products are protein L-glutamate and NH3.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is protein-L-glutamine amidohydrolase. Other names in common use include peptidoglutaminase II, glutaminyl-peptide glutaminase, destabilase, and peptidylglutaminase II.

References

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