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{{enzyme
| Name = phthalyl amidase
| EC_number = 3.5.1.79
| CAS_number = 169150-79-2
| IUBMB_EC_number = 3/5/1/79
| GO_code = 0047418
| image =
| width =
| caption =
}}
In [[enzymology]], a '''phthalyl amidase''' ({{EC number|3.5.1.79}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]


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:a phthalylamide + H<sub>2</sub>O <math>\rightleftharpoons</math> phthalic acid + a substituted amine
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[phthalylamide]] and [[water|H<sub>2</sub>O]], whereas its two [[product (chemistry)|products]] are [[phthalic acid]] and [[substituted amine]].
 
This enzyme belongs to the family of [[hydrolase]]s, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is '''phthalyl-amide amidohydrolase'''.
 
==References==
{{reflist|1}}
* {{cite journal | author = M | date = 1996 | title = Discovery, purification, and properties of o-phthalyl amidase from Xanthobacter agilis | journal = J. Mol. Catal., B Enzym. | volume = 2 | pages = 53&ndash;69 | doi = 10.1016/1381-1177(96)00011-2 }}
* {{cite journal | author = Zmijewski MJ | date = 1996 | title = o-Phthalyl amidase in the synthesis of Loracarbef: process development using this novel biocatalyst | journal = Biotechnol. Lett. | volume = 18 | pages = 875&ndash;880 | doi = 10.1007/BF00154613 | last2 = Briggs | first2 = Barbara S. | last3 = Evans | first3 = Robert | last4 = Muth | first4 = William L. | last5 = Vangala | first5 = Surya | last6 = Zmijewski | first6 = Milton J. }}
* {{cite journal | author = Costello C, Kreuzman A, Zmijewski M | date = 1996 | title = Selective deprotection of phthalyl protected proteins | journal = Tetrahedron Lett. | volume = 37 | pages = 7469&ndash;7472 }}
* {{cite journal | author = Briggs BS, Zmijewski MJ | date = 1995 | title = Enzyme from microbial source: phthalyl amidase | journal = Chem. Abstr| volume = 123 | pages = 25010 }}
 
{{hydrolase-stub}}
 
[[Category:Hydrolases acting on nonpeptide C-N bonds]]
[[Category:Enzymes of unknown structure]]

Revision as of 08:49, 13 March 2013

Template:Enzyme In enzymology, a phthalyl amidase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

a phthalylamide + H2O phthalic acid + a substituted amine

Thus, the two substrates of this enzyme are phthalylamide and H2O, whereas its two products are phthalic acid and substituted amine.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is phthalyl-amide amidohydrolase.

References

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Template:Hydrolase-stub