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{{enzyme
| Name = peptide-tryptophan 2,3-dioxygenase
| EC_number = 1.13.11.26
| CAS_number = 37256-64-7
| IUBMB_EC_number = 1/13/11/26
| GO_code = 0050169
| image =
| width =
| caption =  
}}
In [[enzymology]], a '''peptide-tryptophan 2,3-dioxygenase''' ({{EC number|1.13.11.26}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:peptide tryptophan + O<sub>2</sub> <math>\rightleftharpoons</math> peptide formylkynurenine
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[peptide tryptophan]] and [[oxygen|O<sub>2</sub>]], whereas its [[product (chemistry)|product]] is [[peptide formylkynurenine]].
 
This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on single donors with O<sub>2</sub> as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O<sub>2</sub>. The systematic name of this enzyme class is '''peptide-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)'''. Other names in common use include '''pyrrolooxygenase''', '''peptidyltryptophan 2,3-dioxygenase''', and '''tryptophan pyrrolooxygenase'''.
 
==References==
{{reflist|1}}
* {{cite journal | author = Frydman RB, Tomaro ML, Frydman B | date = 1972 | title = Pyrrolooxygenase: its action on tryptophan-containing enzymes and peptides | journal = Biochim. Biophys. Acta. | volume = 284 | pages = 80&ndash;9  | pmid = 4403729 | issue = 1 }}
 
{{1.13-enzyme-stub}}
 
[[Category:EC 1.13.11]]
[[Category:Enzymes of unknown structure]]

Latest revision as of 03:55, 2 March 2013

Template:Enzyme In enzymology, a peptide-tryptophan 2,3-dioxygenase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

peptide tryptophan + O2 peptide formylkynurenine

Thus, the two substrates of this enzyme are peptide tryptophan and O2, whereas its product is peptide formylkynurenine.

This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2. The systematic name of this enzyme class is peptide-tryptophan:oxygen 2,3-oxidoreductase (decyclizing). Other names in common use include pyrrolooxygenase, peptidyltryptophan 2,3-dioxygenase, and tryptophan pyrrolooxygenase.

References

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