Phosphonate dehydrogenase: Difference between revisions

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{{enzyme
| Name = cob(II)alamin reductase
| EC_number = 1.16.1.4
| CAS_number = 37256-40-9
| IUBMB_EC_number = 1/16/1/4
| GO_code = 0050453
| image =
| width =
| caption =
}}
In [[enzymology]], a '''cob(II)alamin reductase''' ({{EC number|1.16.1.4}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:2 cob(I)alamin + NAD<sup>+</sup> <math>\rightleftharpoons</math> 2 cob(II)alamin + NADH + H<sup>+</sup>
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[cob(I)alamin]] and [[nicotinamide adenine dinucleotide|NAD<sup>+</sup>]], whereas its 3 [[product (chemistry)|products]] are [[cob(II)alamin]], [[nicotinamide adenine dinucleotide|NADH]], and [[hydrogen ion|H<sup>+</sup>]].
 
This enzyme belongs to the family of [[oxidoreductase]]s, specifically those oxidizing metal ion with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is '''cob(I)alamin:NAD+ oxidoreductase'''. Other names in common use include '''vitamin B12r reductase''', '''B12r reductase''', and '''NADH2:cob(II)alamin oxidoreductase'''. This enzyme participates in [[porphyrin and chlorophyll metabolism]]. It employs one [[cofactor (biochemistry)|cofactor]], [[FAD]].
 
==References==
{{reflist|1}}
* {{cite journal | author = Walker GA, Murphy S, Huennekens FM | date = 1969 | title = Enzymatic conversion of vitamin B 12a to adenosyl-B 12: evidence for the existence of two separate reducing systems | journal = Arch. Biochem. Biophys. | volume = 134 | pages = 95&ndash;102  | pmid = 4390543 | doi = 10.1016/0003-9861(69)90255-0 | issue = 1 }}
 
{{1.16-enzyme-stub}}
 
[[Category:EC 1.16.1]]
[[Category:NADH-dependent enzymes]]
[[Category:Flavin enzymes]]
[[Category:Enzymes of unknown structure]]

Latest revision as of 03:56, 2 March 2013

Template:Enzyme In enzymology, a cob(II)alamin reductase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

2 cob(I)alamin + NAD+ 2 cob(II)alamin + NADH + H+

Thus, the two substrates of this enzyme are cob(I)alamin and NAD+, whereas its 3 products are cob(II)alamin, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those oxidizing metal ion with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cob(I)alamin:NAD+ oxidoreductase. Other names in common use include vitamin B12r reductase, B12r reductase, and NADH2:cob(II)alamin oxidoreductase. This enzyme participates in porphyrin and chlorophyll metabolism. It employs one cofactor, FAD.

References

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