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{{enzyme
| Name = 2-oxobutyrate synthase
| EC_number = 1.2.7.2
| CAS_number = 37251-04-0
| IUBMB_EC_number = 1/2/7/2
| GO_code = 0018491
| image =
| width =
| caption =
}}
In [[enzymology]], a '''2-oxobutyrate synthase''' ({{EC number|1.2.7.2}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:2-oxobutanoate + CoA + oxidized ferredoxin <math>\rightleftharpoons</math> propanoyl-CoA + CO<sub>2</sub> + reduced ferredoxin
 
The 3 [[substrate (biochemistry)|substrates]] of this enzyme are [[2-oxobutanoate]], [[coenzyme A|CoA]], and [[oxidized ferredoxin]], whereas its 3 [[product (chemistry)|products]] are [[propanoyl-CoA]], [[carbon dioxide|CO<sub>2</sub>]], and [[reduced ferredoxin]].
 
This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the aldehyde or oxo group of donor with an iron-sulfur protein as acceptor. The systematic name of this enzyme class is '''2-oxobutanoate:ferredoxin 2-oxidoreductase (CoA-propanoylating)'''. Other names in common use include '''alpha-ketobutyrate-ferredoxin oxidoreductase''', '''2-ketobutyrate synthase''', '''alpha-ketobutyrate synthase''', '''2-oxobutyrate-ferredoxin oxidoreductase''', and '''2-oxobutanoate:ferredoxin 2-oxidoreductase (CoA-propionylating)'''. This enzyme participates in [[propanoate metabolism]].
 
==References==
{{reflist|1}}
* {{cite journal | author = Buchanan BB | date = 1969 | title = Role of ferredoxin in the synthesis of alpha-ketobutyrate from propionyl coenzyme A and carbon dioxide by enzymes from photosynthetic and nonphotosynthetic bacteria | journal = J. Biol. Chem. | volume = 244 | pages = 4218&ndash;23  | pmid = 5800441 | issue = 15 }}
 
{{1.2-enzyme-stub}}
 
[[Category:EC 1.2.7]]
[[Category:Enzymes of unknown structure]]

Latest revision as of 03:53, 2 March 2013

Template:Enzyme In enzymology, a 2-oxobutyrate synthase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

2-oxobutanoate + CoA + oxidized ferredoxin propanoyl-CoA + CO2 + reduced ferredoxin

The 3 substrates of this enzyme are 2-oxobutanoate, CoA, and oxidized ferredoxin, whereas its 3 products are propanoyl-CoA, CO2, and reduced ferredoxin.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with an iron-sulfur protein as acceptor. The systematic name of this enzyme class is 2-oxobutanoate:ferredoxin 2-oxidoreductase (CoA-propanoylating). Other names in common use include alpha-ketobutyrate-ferredoxin oxidoreductase, 2-ketobutyrate synthase, alpha-ketobutyrate synthase, 2-oxobutyrate-ferredoxin oxidoreductase, and 2-oxobutanoate:ferredoxin 2-oxidoreductase (CoA-propionylating). This enzyme participates in propanoate metabolism.

References

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