Questin monooxygenase: Difference between revisions

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{{enzyme
| Name = (S)-limonene 3-monooxygenase
| EC_number = 1.14.13.47
| CAS_number = 138066-92-9
| IUBMB_EC_number = 1/14/13/47
| GO_code = 0018674
| image =
| width =
| caption =
}}
In [[enzymology]], a '''(S)-limonene 3-monooxygenase''' ({{EC number|1.14.13.47}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]


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:(-)-(S)-limonene + NADPH + H<sup>+</sup> + O<sub>2</sub> <math>\rightleftharpoons</math> (-)-trans-isopiperitenol + NADP<sup>+</sup> + H<sub>2</sub>O
 
The 4 [[substrate (biochemistry)|substrates]] of this enzyme are [[(-)-(S)-limonene]], [[nicotinamide adenine dinucleotide phosphate|NADPH]], [[hydrogen ion|H<sup>+</sup>]], and [[oxygen|O<sub>2</sub>]], whereas its 3 [[product (chemistry)|products]] are [[(-)-trans-isopiperitenol]], [[nicotinamide adenine dinucleotide phosphate|NADP<sup>+</sup>]], and [[water|H<sub>2</sub>O]].
 
This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. The systematic name of this enzyme class is '''(S)-limonene,NADPH:oxygen oxidoreductase (3-hydroxylating)'''. Other names in common use include '''(-)-limonene 3-hydroxylase''', '''(-)-limonene 3-monooxygenase''', and '''(-)-limonene,NADPH:oxygen oxidoreductase (3-hydroxylating)'''. This enzyme participates in [[monoterpenoid biosynthesis]].  It employs one [[cofactor (biochemistry)|cofactor]], [[heme]].   
 
==References==
{{reflist|1}}
* {{cite journal | author = Karp F, Mihaliak CA, Harris JL, Croteau R | date = 1990 | title = Monoterpene biosynthesis: specificity of the hydroxylations of (-)-limonene by enzyme preparations from peppermint (Mentha piperita), spearmint (Mentha spicata), and perilla (Perilla frutescens) leaves | journal = Arch. Biochem. Biophys.  | volume = 276 | pages = 219&ndash;26  | pmid = 2297225 | doi = 10.1016/0003-9861(90)90029-X | issue = 1 }}
 
{{1.14.13-enzyme-stub}}
 
[[Category:EC 1.14.13]]
[[Category:NADPH-dependent enzymes]]
[[Category:Heme enzymes]]
[[Category:Enzymes of unknown structure]]

Latest revision as of 03:46, 2 March 2013

Template:Enzyme In enzymology, a (S)-limonene 3-monooxygenase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

(-)-(S)-limonene + NADPH + H+ + O2 ⇌ (-)-trans-isopiperitenol + NADP+ + H2O

The 4 substrates of this enzyme are (-)-(S)-limonene, NADPH, H+, and O2, whereas its 3 products are (-)-trans-isopiperitenol, NADP+, and H2O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. The systematic name of this enzyme class is (S)-limonene,NADPH:oxygen oxidoreductase (3-hydroxylating). Other names in common use include (-)-limonene 3-hydroxylase, (-)-limonene 3-monooxygenase, and (-)-limonene,NADPH:oxygen oxidoreductase (3-hydroxylating). This enzyme participates in monoterpenoid biosynthesis. It employs one cofactor, heme.

References

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