Licodione synthase

Template:Enzyme In enzymology, a methyltetrahydroprotoberberine 14-monooxygenase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

(S)-N-methylcanadine + NADPH + H⁺ + O₂ $\rightleftharpoons$ allocryptopine + NADP⁺ + H₂O

The 4 substrates of this enzyme are (S)-N-methylcanadine, NADPH, H⁺, and O₂, whereas its 3 products are allocryptopine, NADP⁺, and H₂O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. The systematic name of this enzyme class is (S)-N-methylcanadine,NADPH:oxygen oxidoreductase (14-hydroxylating). Other names in common use include methyltetrahydroprotoberberine 14-hydroxylase, (S)-cis-N-methyltetrahydroberberine 14-monooxygenase, and (S)-cis-N-methyltetrahydroprotoberberine-14-hydroxylase. This enzyme participates in alkaloid biosynthesis i. It employs one cofactor, heme.

References

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