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{{enzyme
| Name = pyrimidodiazepine synthase
| EC_number = 1.5.4.1
| CAS_number = 93586-06-2
| IUBMB_EC_number = 1/5/4/1
| GO_code = 0004734
| image =
| width =
| caption =
}}
In [[enzymology]], a '''pyrimidodiazepine synthase''' ({{EC number|1.5.4.1}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:a pyrimidodiazepine + glutathione disulfide + H<sub>2</sub>O <math>\rightleftharpoons</math> 6-pyruvoyltetrahydropterin + 2 glutathione
 
The 3 [[substrate (biochemistry)|substrates]] of this enzyme are [[pyrimidodiazepine]], [[glutathione disulfide]], and [[water|H<sub>2</sub>O]], whereas its two [[product (chemistry)|products]] are [[6-pyruvoyltetrahydropterin]] and [[glutathione]].
 
This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the CH-NH group of donors with a disulfide as acceptor. The systematic name of this enzyme class is '''pyrimidodiazepine:glutathione-disulfide oxidoreductase (ring-opening, cyclizing)'''. Other names in common use include '''PDA synthase''', '''pyrimidodiazepine:oxidized-glutathione oxidoreductase (ring-opening,''', and '''cyclizing)'''.  This enzyme participates in [[glutathione metabolism]]
 
==References==
{{reflist|1}}
* {{cite journal | author = Wiederrecht GJ, Brown GM | date = 1984 | title = Purification and properties of the enzymes from Drosophila melanogaster that catalyze the conversion of dihydroneopterin triphosphate to the pyrimidodiazepine precursor of the drosopterins | journal = J. Biol. Chem. | volume = 259 | pages = 14121&ndash;7  | pmid = 6438092 | issue = 22 }}
 
{{1.5-enzyme-stub}}
 
[[Category:EC 1.5.4]]
[[Category:Enzymes of unknown structure]]

Revision as of 06:22, 8 January 2014

Template:Enzyme In enzymology, a pyrimidodiazepine synthase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

a pyrimidodiazepine + glutathione disulfide + H2O 6-pyruvoyltetrahydropterin + 2 glutathione

The 3 substrates of this enzyme are pyrimidodiazepine, glutathione disulfide, and H2O, whereas its two products are 6-pyruvoyltetrahydropterin and glutathione.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with a disulfide as acceptor. The systematic name of this enzyme class is pyrimidodiazepine:glutathione-disulfide oxidoreductase (ring-opening, cyclizing). Other names in common use include PDA synthase, pyrimidodiazepine:oxidized-glutathione oxidoreductase (ring-opening,, and cyclizing). This enzyme participates in glutathione metabolism.

References

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