Propanediol-phosphate dehydrogenase: Difference between revisions

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== Buy New Balance  and crying. Ask the Wilpons. Once created ==
{{DISPLAYTITLE:Glycerol-1-phosphate dehydrogenase (NAD(P)<sup>+</sup>)}}
{{enzyme
| Name = glycerol-1-phosphate dehydrogenase [NAD(P)<sup>+</sup>]
| EC_number = 1.1.1.261
| CAS_number = 204594-18-3
| IUBMB_EC_number = 1/1/1/261
| GO_code = 0050492
| image =
| width =  
| caption =  
}}
In [[enzymology]], a '''glycerol-1-phosphate dehydrogenase [NAD(P)<sup>+</sup>]''' ({{EC number|1.1.1.261}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]


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:sn-glycerol-1-phosphate + NAD(P)<sup>+</sup> <math>\rightleftharpoons</math> glycerone phosphate + NAD(P)H + H<sup>+</sup>
 
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The 3 [[substrate (biochemistry)|substrates]] of this enzyme are [[sn-glycerol-1-phosphate]], [[nicotinamide adenine dinucleotide|NAD<sup>+</sup>]], and [[nicotinamide adenine dinucleotide phosphate|NADP<sup>+</sup>]], whereas its 4 [[product (chemistry)|products]] are [[glycerone phosphate]], [[nicotinamide adenine dinucleotide|NADH]], [[nicotinamide adenine dinucleotide phosphate|NADPH]], and [[hydrogen ion|H<sup>+</sup>]].


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This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the CH-OH group of donor with NAD<sup>+</sup> or NADP<sup>+</sup> as acceptor. The systematic name of this enzyme class is '''sn-glycerol-1-phosphate:NAD(P)<sup>+</sup> 2-oxidoreductase'''. This enzyme is also called '''glycerol-1-phosphate dehydrogenase [NAD(P)<sup>+</sup>]'''.
 
 
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G-1-P dehydrogenase is responsible for the formation of ''sn''-glycerol-1-phosphate, the backbone of the membrane phospholipids of Archaea. The gene encoding glycerol-1-phosphate dehydrogenase has been detected in all the archaeal species and has not been found in any bacterial or eukaryal species. ''sn''-glycerol-1-phosphate produced by this enzyme is the most fundamental difference by which Archaea and bacteria are discriminated.
 
 
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==References==
 
{{reflist|1}}
  <li>[http://pedagogie-differenciee.eu/spip.php?page=auteur&id_auteur=1&lang=fr/ http://pedagogie-differenciee.eu/spip.php?page=auteur&id_auteur=1&lang=fr/]</li>
* {{cite journal | author = Koga Y, Kyuragi T, Nishihara M, Sone N | year = 1998 | title = Did archaeal and bacterial cells arise independently from noncellular precursors? A hypothesis stating that the advent of membrane phospholipid with enantiomeric glycerophosphate backbones caused the separation of the two lines of descent | journal = J. Mol. Evol. | volume = 46 | pages = 54&ndash;63 | pmid = 9419225 | doi = 10.1007/PL00006283 | issue = 1 }}
 
 
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[[Category:EC 1.1.1]]
 
[[Category:NADPH-dependent enzymes]]
  <li>[http://www.nmmxc.com/bbs/forum.php?mod=viewthread&tid=2264711 http://www.nmmxc.com/bbs/forum.php?mod=viewthread&tid=2264711]</li>
[[Category:NADH-dependent enzymes]]
 
[[Category:Enzymes of unknown structure]]
</ul>
 
 
{{1.1.1-enzyme-stub}}

Latest revision as of 15:55, 2 June 2013

Template:Enzyme In enzymology, a glycerol-1-phosphate dehydrogenase [NAD(P)+] (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

sn-glycerol-1-phosphate + NAD(P)+ glycerone phosphate + NAD(P)H + H+

The 3 substrates of this enzyme are sn-glycerol-1-phosphate, NAD+, and NADP+, whereas its 4 products are glycerone phosphate, NADH, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is sn-glycerol-1-phosphate:NAD(P)+ 2-oxidoreductase. This enzyme is also called glycerol-1-phosphate dehydrogenase [NAD(P)+].

G-1-P dehydrogenase is responsible for the formation of sn-glycerol-1-phosphate, the backbone of the membrane phospholipids of Archaea. The gene encoding glycerol-1-phosphate dehydrogenase has been detected in all the archaeal species and has not been found in any bacterial or eukaryal species. sn-glycerol-1-phosphate produced by this enzyme is the most fundamental difference by which Archaea and bacteria are discriminated.

References

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