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| {{enzyme
| | Hi, everybody! My name is Genie. <br>It is a little about myself: I live in Netherlands, my city of Groningen. <br>It's called often Northern or cultural capital of GR. I've married 4 years ago.<br>I have 2 children - a son (Brianna) and the daughter (Edison). We all like Australian Football League.<br><br>Review my site ... [http://greatlakes.n49.ca/ Great Lakes Biodiesel Inc Toronto] |
| | Name = Pyridoxal phosphatase
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| | EC_number = 3.1.3.74
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| | CAS_number =
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| | IUBMB_EC_number = 3/1/3/74
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| | GO_code =
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| In [[enzymology]], a '''pyridoxal phosphatase''' ({{EC number|3.1.3.74}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
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| :pyridoxal 5'-phosphate + H<sub>2</sub>O <math>\rightleftharpoons</math> pyridoxal + phosphate | |
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| Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[pyridoxal 5'-phosphate]] and [[water|H<sub>2</sub>O]], whereas its two [[product (chemistry)|products]] are [[pyridoxal]] and [[phosphate]].
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| This enzyme belongs to the family of [[hydrolase]]s, specifically those acting on phosphoric [[ester|monoester]] bonds. The systematic name of this enzyme class is '''pyridoxal-5'-phosphate phosphohydrolase'''. Other names in common use include '''vitamine B<sub>6</sub> (pyridoxine) phosphatase''', '''PLP phosphatase''', '''vitamin B<sub>6</sub>-phosphate phosphatase''', and '''PNP phosphatase'''. This enzyme participates in vitamin B<sub>6</sub> metabolism.
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| ==Structural studies==
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| As of late 2007, 6 [[tertiary structure|structures]] have been solved for this class of enzymes, with [[Protein Data Bank|PDB]] accession codes {{PDB link|2CFR}}, {{PDB link|2CFS}}, {{PDB link|2CFT}}, {{PDB link|2OYC}}, {{PDB link|2P27}}, and {{PDB link|2P69}}.
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| ==References==
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| {{reflist|1}}
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| * {{cite journal | author = Fonda ML | date = 1992 | title = Purification and characterization of vitamin B<sub>6</sub>-phosphate phosphatase from human erythrocytes | journal = J. Biol. Chem. | volume = 267 | pages = 15978–83 | pmid = 1322411 | issue = 22 }}
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| * {{cite journal | author = Fonda ML, Zhang YN | date = 1995 | title = Kinetic mechanism and divalent metal activation of human erythrocyte pyridoxal phosphatase | journal = Arch. Biochem. Biophys. | volume = 320 | pages = 345–52 | pmid = 7625842 | doi = 10.1016/0003-9861(95)90018-7 | issue = 2 }}
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| * {{cite journal | author = OS | date = 2003 | title = Human pyridoxal phosphatase. Molecular cloning, functional expression, and tissue distribution | journal = J. Biol. Chem. | volume = 278 | pages = 50040–6 | pmid = 14522954 | doi = 10.1074/jbc.M309619200 | last2 = Kim | first2 = DW | last3 = Kang | first3 = TC | last4 = Won | first4 = MH | last5 = Baek | first5 = NI | last6 = Moon | first6 = BJ | last7 = Choi | first7 = SY | last8 = Kwon | first8 = OS | issue = 50 }}
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| {{hydrolase-stub}}
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| [[Category:EC 3.1.3]]
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| [[Category:Enzymes of known structure]]
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Hi, everybody! My name is Genie.
It is a little about myself: I live in Netherlands, my city of Groningen.
It's called often Northern or cultural capital of GR. I've married 4 years ago.
I have 2 children - a son (Brianna) and the daughter (Edison). We all like Australian Football League.
Review my site ... Great Lakes Biodiesel Inc Toronto