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{{enzyme
| Name = chitin synthase
| EC_number = 2.4.1.16
| CAS_number = 9030-18-6
| IUBMB_EC_number = 2/4/1/16
| GO_code = 0004100
| image =
| width =
| caption =
}}
In [[enzymology]], a '''chitin synthase''' ({{EC number|2.4.1.16}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:UDP-N-acetyl-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n <math>\rightleftharpoons</math> UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n<sup>+</sup>1
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[UDP-N-acetyl-D-glucosamine]] and [[[1,4-(N-acetyl-beta-D-glucosaminyl)]n]], whereas its two [[product (chemistry)|products]] are [[uridine diphosphate|UDP]] and [[[1,4-(N-acetyl-beta-D-glucosaminyl)]n+1]].
 
This enzyme belongs to the family of [[glycosyltransferase]]s, specifically the hexosyltransferases. The systematic name of this enzyme class is '''UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase'''. Other names in common use include '''chitin-UDP N-acetylglucosaminyltransferase''', '''chitin-uridine diphosphate acetylglucosaminyltransferase''', '''chitin synthetase''', and '''trans-N-acetylglucosaminosylase'''. This enzyme participates in [[aminosugars metabolism]].
 
==Production==
Chitin Synthase is manufactured in the [[rough endoplasmic reticulum]] of fungi as the inactive form, [[zymogen]]. The zymogen is then packaged into chitosomes in the [[golgi apparatus]]. Chitosomes bring the zymogen to the [[hyphal]] tip of a mold or yeast cell membrane. Chitin synthase is placed into the interior side of the cell membrane and then activated.{{Citation needed|date=October 2011}}
 
==References==
{{reflist|1}}
* {{cite journal | author = GLASER L, BROWN DH | date = 1957 | title = The synthesis of chitin in cell-free extracts of Neurospora crassa | journal = J. Biol. Chem. | volume = 228 | pages = 729&ndash;42  | pmid = 13475355 | issue = 2 }}
* {{cite journal | author = Sburlati A, Cabib E | date = 1986 | title = Chitin synthetase 2, a presumptive participant in septum formation in Saccharomyces cerevisiae | journal = J. Biol. Chem. | volume = 261 | pages = 15147&ndash;52  | pmid = 2945823 | issue = 32 }}
 
{{enzyme-stub}}
 
[[Category:EC 2.4.1]]
[[Category:Enzymes of unknown structure]]

Latest revision as of 12:43, 23 January 2014

Template:Enzyme In enzymology, a chitin synthase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

UDP-N-acetyl-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1

Thus, the two substrates of this enzyme are UDP-N-acetyl-D-glucosamine and [[[1,4-(N-acetyl-beta-D-glucosaminyl)]n]], whereas its two products are UDP and [[[1,4-(N-acetyl-beta-D-glucosaminyl)]n+1]].

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase. Other names in common use include chitin-UDP N-acetylglucosaminyltransferase, chitin-uridine diphosphate acetylglucosaminyltransferase, chitin synthetase, and trans-N-acetylglucosaminosylase. This enzyme participates in aminosugars metabolism.

Production

Chitin Synthase is manufactured in the rough endoplasmic reticulum of fungi as the inactive form, zymogen. The zymogen is then packaged into chitosomes in the golgi apparatus. Chitosomes bring the zymogen to the hyphal tip of a mold or yeast cell membrane. Chitin synthase is placed into the interior side of the cell membrane and then activated.Potter or Ceramic Artist Truman Bedell from Rexton, has interests which include ceramics, best property developers in singapore developers in singapore and scrabble. Was especially enthused after visiting Alejandro de Humboldt National Park.

References

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Template:Enzyme-stub