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| {{enzyme
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| | Name = acylglycerone-phosphate reductase
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| | EC_number = 1.1.1.101
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| | CAS_number = 37250-35-4
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| | IUBMB_EC_number = 1/1/1/101
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| | GO_code = 0000140
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| In [[enzymology]], an '''acylglycerone-phosphate reductase''' ({{EC number|1.1.1.101}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
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| :1-palmitoylglycerol 3-phosphate + NADP<sup>+</sup> <math>\rightleftharpoons</math> palmitoylglycerone phosphate + NADPH + H<sup>+</sup>
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| Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[1-palmitoylglycerol 3-phosphate]] and [[nicotinamide adenine dinucleotide phosphate|NADP<sup>+</sup>]], whereas its 3 [[product (chemistry)|products]] are [[palmitoylglycerone phosphate]], [[nicotinamide adenine dinucleotide phosphate|NADPH]], and [[hydrogen ion|H<sup>+</sup>]].
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| This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the CH-OH group of donor with NAD<sup>+</sup> or NADP<sup>+</sup> as acceptor. The systematic name of this enzyme class is '''1-palmitoylglycerol-3-phosphate:NADP<sup>+</sup> oxidoreductase'''. Other names in common use include '''palmitoyldihydroxyacetone-phosphate reductase''', '''palmitoyl dihydroxyacetone phosphate reductase''', '''palmitoyl-dihydroxyacetone-phosphate reductase''', '''acyldihydroxyacetone phosphate reductase''', and '''palmitoyl dihydroxyacetone phosphate reductase'''. This enzyme participates in [[glycerophospholipid]] and [[ether lipid]] metabolism.
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| ==References== | |
| {{reflist|1}}
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| * {{cite journal | author = LaBelle EF Jr, Hajra AK | date = 1972 | title = Enzymatic reduction of alkyl and acyl derivatives of dihydroxyacetone phosphate by reduced pyridine nucleotides | journal = J. Biol. Chem. | volume = 247 | pages = 5825–34 | pmid = 4403490 | issue = 18 }}
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| [[Category:EC 1.1.1]]
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| [[Category:NADPH-dependent enzymes]]
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| [[Category:Enzymes of unknown structure]]
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| {{1.1.1-enzyme-stub}}
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Latest revision as of 12:06, 23 August 2014
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