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| {{Infobox enzyme
| | She is known by the title of Myrtle Shryock. He is really fond of performing ceramics but he is having difficulties to find time for it. Since she was 18 she's been working as a meter reader but she's usually wanted her personal business. For a whilst I've been in South Dakota and my mothers and fathers live nearby.<br><br>Feel free to surf to my blog [http://xrambo.com/blog/191590 xrambo.com] |
| | Name = Site-specific DNA-methyltransferase (cytosine-N4-specific)
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| | EC_number = 2.1.1.113
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| | CAS_number = 169592-50-1
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| | IUBMB_EC_number = 2/1/1/113
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| | GO_code =
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| '''Site-specific DNA-methyltransferase (cytosine-N4-specific)''' ({{EC number|2.1.1.113}}, ''modification methylase'', ''restriction-modification system'', ''DNA[cytosine-N4]methyltransferase'', ''m4C-forming MTase'', ''S-adenosyl-L-methionine:DNA-cytosine 4-N-methyltransferase'') is an [[enzyme]] with system name ''S-adenosyl-L-methionine:DNA-cytosine N4-methyltransferase''.<ref>{{cite journal | title = Specificity of restriction endonucleases and DNA modification methyltransferases: a review |author = Kessler, C. and Manta, V. |journal = Gene |date = 1990 |volume = 92 |pages = 1-248 |pmid = 2172084 |doi=10.1016/0378-1119(90)90486-B}}</ref><ref>{{cite journal | title = Sequence motifs characteristic of DNA[cytosine-N4]methyltransferases: similarity to adenine and cytosine-C5 DNA-methylases |author = Klimasauskas, S., Timinskas, A., Menkevicius, S., Butkiene, D., Butkus, V. and Janulaitis, A. |journal = Nucleic Acids Res. |date = 1989 |volume = 17 |pages = 9823-9832 |pmid = 2690010 |doi=10.1093/nar/17.23.9823}}</ref><ref>{{cite journal | title = Restriction enzymes and their isoschizomers |author = Roberts, R.J. |journal = Nucleic Acids Res. |date = 1990 |volume = 18 |pages = 2331-2365 |pmid = 2159140 |doi=10.1093/nar/18.suppl.2331}}</ref><ref>{{cite journal | title = Structure and mechanism of multifunctional restriction endonucleases |author = Yuan, R. |journal = Annu. Rev. Biochem. |date = 1981 |volume = 50 |pages = 285-319 |pmid = 6267988 |doi=10.1146/annurev.bi.50.070181.001441}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]
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| : S-adenosyl-L-methionine + DNA cytosine <math>\rightleftharpoons</math> S-adenosyl-L-homocysteine + DNA N4-methylcytosine
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| This is a large group of enzymes.<ref>{{cite web |url = http://rebase.neb.com/rebase/rebase.html |title = A complete listing of all of these enzymes |author = R.J. Roberts}}</ref>
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| == References ==
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| {{reflist}}
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| == See also ==
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| * [[DNA methyltransferase]]
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| == External links ==
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| * {{MeshName|Site-specific+DNA-methyltransferase+(cytosine-N4-specific)}}
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| [[Category:EC 2.1.1]]
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Latest revision as of 08:09, 17 December 2014
She is known by the title of Myrtle Shryock. He is really fond of performing ceramics but he is having difficulties to find time for it. Since she was 18 she's been working as a meter reader but she's usually wanted her personal business. For a whilst I've been in South Dakota and my mothers and fathers live nearby.
Feel free to surf to my blog xrambo.com