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	<title>Tobler&#039;s hiking function - Revision history</title>
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	<updated>2026-08-03T23:34:45Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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		<id>https://en.formulasearchengine.com/w/index.php?title=Tobler%27s_hiking_function&amp;diff=29164&amp;oldid=prev</id>
		<title>en&gt;David Eppstein: {{applied-math-stub}}</title>
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		<updated>2013-10-14T07:05:25Z</updated>

		<summary type="html">&lt;p&gt;{{applied-math-stub}}&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;{{Infobox enzyme&lt;br /&gt;
| Name = 2&amp;#039;-Deamino-2&amp;#039;-hydroxyneamine transaminase&lt;br /&gt;
| EC_number = 2.6.1.94&lt;br /&gt;
| CAS_number = &lt;br /&gt;
| IUBMB_EC_number = 2/6/1/94&lt;br /&gt;
| GO_code = &lt;br /&gt;
| image = &lt;br /&gt;
| width = &lt;br /&gt;
| caption =&lt;br /&gt;
}}&lt;br /&gt;
&amp;#039;&amp;#039;&amp;#039;2&amp;#039;-Deamino-2&amp;#039;-hydroxyneamine transaminase&amp;#039;&amp;#039;&amp;#039; ({{EC number|2.6.1.94}}, &amp;#039;&amp;#039;kacL (gene)&amp;#039;&amp;#039;) is an [[enzyme]] with system name &amp;#039;&amp;#039;2&amp;#039;-deamino-2&amp;#039;-hydroxyneamine:2-oxoglutarate aminotransferase&amp;#039;&amp;#039;.&amp;lt;ref&amp;gt;{{cite journal | title = Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation |author = Park, J.W., Park, S.R., Nepal, K.K., Han, A.R., Ban, Y.H., Yoo, Y.J., Kim, E.J., Kim, E.M., Kim, D., Sohng, J.K. and Yoon, Y.J. |journal = Nat. Chem. Biol. |year = 2011 |volume = 7 |pages = 843–852 |pmid = 21983602 |doi=10.1038/nchembio.671}}&amp;lt;/ref&amp;gt; This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]&lt;br /&gt;
&lt;br /&gt;
: 2&amp;#039;-deamino-2&amp;#039;-hydroxyneamine + [[2-oxoglutarate]] &amp;lt;math&amp;gt;\rightleftharpoons&amp;lt;/math&amp;gt; 2&amp;#039;-deamino-2&amp;#039;-hydroxy-6&amp;#039;-dehydroparomamine + L-[[glutamate]]&lt;br /&gt;
&lt;br /&gt;
The reaction occurs &amp;#039;&amp;#039;[[in vivo]]&amp;#039;&amp;#039; in the opposite direction.&lt;br /&gt;
== References ==&lt;br /&gt;
{{reflist}}&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
* {{MeshName|2&amp;#039;-deamino-2&amp;#039;-hydroxyneamine+transaminase}}&lt;br /&gt;
&lt;br /&gt;
[[Category:EC 2.6.1]]&lt;/div&gt;</summary>
		<author><name>en&gt;David Eppstein</name></author>
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