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fixed CS1 errors: dates to meet MOS:DATEFORMAT (also General fixes) using AWB (10331)

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	~~\| Name = deoxycytidylate 5-hydroxymethyltransferase~~
	~~\| EC_number = 2~~.1.2.8
	~~\| CAS_number = 9012~~-68-4
	~~\| IUBMB_EC_number = 2/1/2/8~~
	~~\| GO_code = 0047153~~
	~~\| image =~~
	~~\| width =~~
	~~\| caption =~~
	}}
	~~In [[enzymology]]~~, a '~~''deoxycytidylate 5-hydroxymethyltransferase''' ({{EC number\|2~~.1.2.~~8}})~~ is ~~an [[enzyme]]~~ that ~~[[catalysis\|catalyzes]]~~ the ~~[[chemical reaction]]~~

	~~:5,10-methylenetetrahydrofolate + H~~<~~sub~~>2<~~/sub~~>~~O + deoxycytidylate~~ <~~math~~>~~\rightleftharpoons~~<~~/math~~> ~~tetrahydrofolate + 5~~-~~hydroxymethyldeoxycytidylate~~

	~~The 3~~ [~~[substrate (biochemistry)\|substrates]~~] of ~~this enzyme are [[5~~,~~10-methylenetetrahydrofolate]]~~, ~~[[water\|H~~<~~sub~~>2<~~/sub~~>~~O]]~~, and ~~[[deoxycytidylate]]~~, ~~whereas its two [[product (chemistry)\|products]]~~ are ~~[[tetrahydrofolate]] and [[5-hydroxymethyldeoxycytidylate]]~~.

	~~This enzyme belongs~~ to ~~the~~ family of [~~[transferase~~]~~]s that transfer one-carbon groups~~, ~~specifically the hydroxymethyl-~~, ~~formyl-~~ and ~~related transferases~~. The ~~systematic name~~ of ~~this enzyme class is '''5~~,~~10-methylenetetrahydrofolate:deoxycytidylate 5-hydroxymethyltransferase'''~~. ~~Other names in common use include '''dCMP hydroxymethylase'''~~, ~~'''d-cytidine 5'-monophosphate hydroxymethylase'''~~, ~~'''deoxyCMP hydroxymethylase''', '''deoxycytidylate hydroxymethylase'''~~, and ~~'''deoxycytidylic hydroxymethylase'''~~. ~~This enzyme participates in~~ [[~~pyrimidine metabolism~~]~~] and~~ [[~~one carbon pool by folate]]~~.

	==~~Structural studies~~==

	~~As of late 2007, 3 [[tertiary structure\|structures~~]] ~~have been solved for this class~~ of ~~enzymes, with~~ [~~[Protein Data Bank\|PDB~~]~~] accession codes {{PDB link\|1B49}}, {{PDB link\|1B5D}},~~ and ~~{{PDB link\|1B5E}}~~.

	~~==References==~~
	~~{{reflist\|1}}~~
	* {{cite journal \| author = Mathews CK, Brown F and ~~Cohen SS \| date = 1964 \| title = Virus-induced acquisition of metabolic function~~. ~~VII~~. ~~Biosynthesis de novo~~ of ~~deoxycytidylate hydroxymethylase \| journal = J~~. ~~Biol~~. ~~Chem~~. ~~\| volume = 239 \| pages = 2957–2963 }}~~

	~~{{transferase-stub}}~~

	[~~[Category~~:~~EC 2~~.1.2]]
	~~[[Category:Enzymes~~ of ~~known structure]]~~

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Strictosidine synthase - Revision history

en>BattyBot: fixed CS1 errors: dates to meet MOS:DATEFORMAT (also General fixes) using AWB (10331)

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