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	<title>Hasse derivative - Revision history</title>
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	<updated>2026-08-31T12:17:25Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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		<title>en&gt;Pinethicket: Undid revision 561575529 by 166.205.55.17 (talk)  stray comment</title>
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		<updated>2013-06-25T20:59:24Z</updated>

		<summary type="html">&lt;p&gt;Undid revision 561575529 by &lt;a href=&quot;/wiki/Special:Contributions/166.205.55.17&quot; title=&quot;Special:Contributions/166.205.55.17&quot;&gt;166.205.55.17&lt;/a&gt; (&lt;a href=&quot;/w/index.php?title=User_talk:166.205.55.17&amp;amp;action=edit&amp;amp;redlink=1&quot; class=&quot;new&quot; title=&quot;User talk:166.205.55.17 (page does not exist)&quot;&gt;talk&lt;/a&gt;)  stray comment&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;{{Infobox enzyme&lt;br /&gt;
| Name = 16S rRNA pseudouridine&amp;lt;sup&amp;gt;516&amp;lt;/sup&amp;gt; synthase&lt;br /&gt;
| EC_number = 5.4.99.19&lt;br /&gt;
| CAS_number = &lt;br /&gt;
| IUBMB_EC_number = 5/4/99/19&lt;br /&gt;
| GO_code = &lt;br /&gt;
| image = &lt;br /&gt;
| width = &lt;br /&gt;
| caption =&lt;br /&gt;
}}&lt;br /&gt;
&amp;#039;&amp;#039;&amp;#039;16S rRNA pseudouridine&amp;lt;sup&amp;gt;516&amp;lt;/sup&amp;gt; synthase&amp;#039;&amp;#039;&amp;#039; ({{EC number|5.4.99.19}}, &amp;#039;&amp;#039;16S RNA pseudouridine&amp;lt;sup&amp;gt;516&amp;lt;/sup&amp;gt; synthase&amp;#039;&amp;#039;, &amp;#039;&amp;#039;16S PsiI&amp;lt;sup&amp;gt;516&amp;lt;/sup&amp;gt; synthase&amp;#039;&amp;#039;, &amp;#039;&amp;#039;16S RNA Psi&amp;lt;sup&amp;gt;516&amp;lt;/sup&amp;gt; synthase&amp;#039;&amp;#039;, &amp;#039;&amp;#039;RNA pseudouridine synthase RsuA&amp;#039;&amp;#039;, &amp;#039;&amp;#039;RsuA&amp;#039;&amp;#039;, &amp;#039;&amp;#039;16S RNA pseudouridine 516 synthase&amp;#039;&amp;#039;) is an [[enzyme]] with system name &amp;#039;&amp;#039;16S rRNA-uridine&amp;lt;sup&amp;gt;516&amp;lt;/sup&amp;gt; uracil mutase&amp;#039;&amp;#039;.&amp;lt;ref&amp;gt;{{cite journal | title = Purification, cloning, and properties of the 16&amp;#039;&amp;#039;S&amp;#039;&amp;#039; RNA pseudouridine 516 synthase from &amp;#039;&amp;#039;Escherichia coli&amp;#039;&amp;#039; |author = Wrzesinski, J., Bakin, A., Nurse, K., Lane, B.G. and Ofengand, J. |journal = Biochemistry |year = 1995 |volume = 34 |pages = 8904–8913 |pmid = 7612632}}&amp;lt;/ref&amp;gt;&amp;lt;ref&amp;gt;{{cite journal | title = 16S ribosomal RNA pseudouridine synthase RsuA of &amp;#039;&amp;#039;Escherichia coli&amp;#039;&amp;#039;: deletion, mutation of the conserved Asp&amp;lt;sup&amp;gt;102&amp;lt;/sup&amp;gt; residue, and sequence  comparison among all other pseudouridine synthases |author = Conrad, J., Niu, L., Rudd, K., Lane, B.G. and Ofengand, J. |journal = RNA |year = 1999 |volume = 5 |pages = 751–763 |pmid = 10376875}}&amp;lt;/ref&amp;gt;&amp;lt;ref&amp;gt;{{cite journal | title = Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP |author = Sivaraman, J., Sauve, V., Larocque, R., Stura, E.A., Schrag, J.D., Cygler, M. and Matte, A. |journal = Nat. Struct. Biol. |year = 2002 |volume = 9 |pages = 353–358 |pmid = 11953756}}&amp;lt;/ref&amp;gt; This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]&lt;br /&gt;
&lt;br /&gt;
: 16S rRNA uridine&amp;lt;sup&amp;gt;516&amp;lt;/sup&amp;gt; &amp;lt;math&amp;gt;\rightleftharpoons&amp;lt;/math&amp;gt; 16S rRNA pseudouridine&amp;lt;sup&amp;gt;516&amp;lt;/sup&amp;gt;&lt;br /&gt;
&lt;br /&gt;
The enzyme is specific for uridine&amp;lt;sup&amp;gt;516&amp;lt;/sup&amp;gt; in 16S rRNA.&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
{{reflist}}&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
* {{MeshName|16S+rRNA+pseudouridine516+synthase}}&lt;br /&gt;
&lt;br /&gt;
[[Category:EC 5.4.99]]&lt;/div&gt;</summary>
		<author><name>en&gt;Pinethicket</name></author>
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