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{{enzyme
| Name = [protein-PII] uridylyltransferase
| EC_number = 2.7.7.59
| CAS_number = 57657-57-5
| IUBMB_EC_number = 2/7/7/59
| GO_code = 0008773
| image = 
| width = 
| caption = 
}}
In [[enzymology]], a '''[protein-PII] uridylyltransferase''' ({{EC number|2.7.7.59}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:UTP + [protein-PII] <math>\rightleftharpoons</math> diphosphate + uridylyl-[protein-PII]

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[uridine triphosphate|UTP]] and [[Pii nitrogen regulatory proteins|protein-PII]], whereas its two [[product (chemistry)|products]] are [[diphosphate]] and [[uridylyl-[protein-PII]]].

This enzyme belongs to the family of [[transferase]]s, specifically those transferring phosphorus-containing [[nucleotide]] groups ([[nucleotidyltransferase]]s).  The systematic name of this enzyme class is '''UTP:[protein-PII] uridylyltransferase'''. Other names in common use include '''PII uridylyl-transferase''', and '''uridyl removing enzyme'''.  This enzyme participates in [[two-component system - general]].  

==References==
{{reflist|1}}
* {{cite journal | author = Garcia E, Rhee SG | date = 1983 | title = Cascade control of Escherichia coli glutamine synthetase Purification and properties of PII uridylyltransferase and uridylyl-removing enzyme | journal = J. Biol. Chem.  | volume = 258 | pages = 2246&ndash;53  | pmid = 6130097 | issue = 4 }}
* {{cite journal | author = van Heeswijk WC, Rabenberg M, Westerhoff HV, Kahn D | date = 1993 | title = The genes of the glutamine synthetase adenylylation cascade are not regulated by nitrogen in Escherichia coli | journal = Mol. Microbiol.  | volume = 9 | pages = 443&ndash;57  | pmid = 8412694 | doi = 10.1111/j.1365-2958.1993.tb01706.x | issue = 3 }}

[[Category:EC 2.7.7|Protein-PII uridylyltransferase]]
[[Category:Enzymes of unknown structure]]

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