View source for Ecdysone 20-monooxygenase

{{enzyme
| Name = gibberellin 3-beta-dioxygenase
| EC_number = 1.14.11.15
| CAS_number = 116036-68-1
| IUBMB_EC_number = 1/14/11/15
| GO_code = 0016707
| image = 
| width = 
| caption = 
}}
In [[enzymology]], a '''gibberellin 3beta-dioxygenase''' ({{EC number|1.14.11.15}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:gibberellin 20 + 2-oxoglutarate + O<sub>2</sub> <math>\rightleftharpoons</math> gibberellin 1 + succinate + CO<sub>2</sub>

The 3 [[substrate (biochemistry)|substrates]] of this enzyme are [[gibberellin 20]], [[2-oxoglutarate]], and [[oxygen|O<sub>2</sub>]], whereas its 3 [[product (chemistry)|products]] are [[gibberellin 1]], [[succinate]], and [[carbon dioxide|CO<sub>2</sub>]].

This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with 2-oxoglutarate as one donor, and incorporation of one atom o oxygen into each donor.  The systematic name of this enzyme class is '''(gibberellin-20),2-oxoglutarate:oxygen oxidoreductase (3beta-hydroxylating)'''. Other names in common use include '''gibberellin 3beta-hydroxylase''', '''(gibberrellin-20),2-oxoglutarate: oxygen oxidoreductase''', and '''(3beta-hydroxylating)'''.  This enzyme participates in [[diterpenoid biosynthesis]].  It has 2 [[cofactor (biochemistry)|cofactors]]: [[iron]],  and [[Ascorbate]].  

==References==
{{reflist|1}}
* {{cite journal | author = Kwak S-S, Kamiya Y, Sakurai A, Takahishi N and Graebe JE | date = 1988 | title = Partial-purification and characterization of gibberellin 3beta-hydroxylase from immature seeds of Phaseolus vulgaris L | journal = Plant Cell Physiol.  | volume = 29 | pages = 935&ndash;943 }}

{{1.14-enzyme-stub}}

[[Category:EC 1.14.11]]
[[Category:Iron enzymes]]
[[Category:Ascorbate enzymes]]
[[Category:Enzymes of unknown structure]]