15-hydroxyprostaglandin dehydrogenase (NAD+)

2013-12-22T19:33:38Z

86.158.64.240:

{{enzyme
| Name = 2-alkyn-1-ol dehydrogenase
| EC_number = 1.1.1.165
| CAS_number = 54576-94-2
| IUBMB_EC_number = 1/1/1/165
| GO_code = 0047535
| image =
| width =
| caption =
}}
In [[enzymology]], a '''2-alkyn-1-ol dehydrogenase''' ({{EC number|1.1.1.165}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:2-butyne-1,4-diol + NAD+ <math>\rightleftharpoons</math> 4-hydroxy-2-butynal + NADH + H+

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[2-butyne-1,4-diol]] and [[nicotinamide adenine dinucleotide|NAD+]], whereas its 3 [[product (chemistry)|products]] are [[4-hydroxy-2-butynal]], [[nicotinamide adenine dinucleotide|NADH]], and [[hydrogen ion|H+]].

This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is '''2-butyne-1,4-diol:NAD+ 1-oxidoreductase'''.

==References==
{{reflist|1}}
* {{cite journal | author = Miyoshi T, Sato H and Harada T | date = 1974 | title = Purification and characterization of 2-alkyne-1-ol dehydrogenase induced by 2-butene-1,4-diol in ''Fusarium merismoides'' B11 | journal = Biochim. Biophys. Acta | volume = 358 | pages = 231–239 }}

[[Category:EC 1.1.1]]
[[Category:NADH-dependent enzymes]]
[[Category:Enzymes of unknown structure]]

{{1.1.1-enzyme-stub}}

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15-hydroxyprostaglandin dehydrogenase (NAD+)