Inosine kinase

2011-07-05T19:10:57Z

216.195.1.35:

{{enzyme
| Name = lombricine kinase
| EC_number = 2.7.3.5
| CAS_number = 9026-53-3
| IUBMB_EC_number = 2/7/3/5
| GO_code = 0050059
| image =
| width =
| caption =
}}
In [[enzymology]], a '''lombricine kinase''' ({{EC number|2.7.3.5}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:ATP + lombricine <math>\rightleftharpoons</math> ADP + N-phospholombricine

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[adenosine triphosphate|ATP]] and [[lombricine]], whereas its two [[product (chemistry)|products]] are [[adenosine diphosphate|ADP]] and [[N-phospholombricine]].

This enzyme belongs to the family of [[transferase]]s, specifically those transferring phosphorus-containing groups ([[phosphotransferase]]s) with a nitrogenous group as acceptor. The systematic name of this enzyme class is '''ATP:lombricine N-phosphotransferase'''. This enzyme participates in [[glycine, serine and threonine metabolism]].

==References==
{{reflist|1}}
* {{cite journal | author = Gaffney TJ, Rosenberg H, Ennor AH | date = 1964 | title = The purification and properties of adenosine triphosphate-lombricine phosphotransferase | journal = Biochem. J. | volume = 90 | pages = 170–6 | pmid = 5832288 | issue = 1 | pmc = 1202539 }}
* {{cite journal | author = Kassab R, Pradel LA, Nguyen Van Thoai | date = 1965 | title = [ATP:taurocyamine and ATP:lombricine phosphotransferases Purification and study of SH groups] | journal = Biochim. Biophys. Acta. | volume = 99 | pages = 397–405 | pmid = 5840960 | issue = 3 }}
* {{cite journal | author = Pant R | date = 1959 | title = Isolation of lombricine and its enzymatic phosphorylation | journal = Biochem. J. | volume = 73 | pages = 30–33 }}
* {{cite journal | author = van Thoai N, Robin Y, Guillou Y | date = 1972 | title = A new phosphagen, N'-phosphorylguanidinoethylphospho-O-( -N,N-dimethyl)serine (phosphothalassemine) | journal = Biochemistry. | volume = 11 | pages = 3890–5 | pmid = 5079888 | doi = 10.1021/bi00771a009 | issue = 21 }}

{{enzyme-stub}}

[[Category:EC 2.7.3]]
[[Category:Enzymes of unknown structure]]

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Inosine kinase