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Meyer wavelet
2013-03-29T15:54:58Z
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<div>{{Infobox enzyme<br />
| Name = TRNA dimethylallyltransferase<br />
| EC_number = 2.5.1.75<br />
| CAS_number = <br />
| IUBMB_EC_number = 2/5/1/75<br />
| GO_code = <br />
| image = <br />
| width = <br />
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}}<br />
'''TRNA dimethylallyltransferase''' ({{EC number|2.5.1.75}}, ''tRNA prenyltransferase, MiaA, transfer ribonucleate isopentenyltransferase'', ''Delta2-isopentenyl pyrophosphate:tRNA-Delta2-isopentenyl transferase'', ''Delta2-isopentenyl pyrophosphate:transfer ribonucleic acid Delta2-isopentenyltransferase'') is an [[enzyme]] with system name ''dimethylallyl-diphosphate: tRNA dimethylallyltransferase''.<ref>{{cite journal | title = Regulation of substrate recognition by the MiaA tRNA prenyltransferase modification enzyme of ''Escherichia coli'' K-12 |author = Leung, H.C., Chen, Y. and Winkler, M.E. |journal = J. Biol. Chem. |year = 1997 |volume = 272 |pages = 13073–13083 |pmid = 9148919 | doi = 10.1074/jbc.272.20.13073 | issue = 20}}</ref><ref>{{cite journal | title = ''Escherichia coli'' dimethylallyl diphosphate:tRNA dimethylallyltransferase: essential elements for recognition of tRNA substrates within the anticodon stem-loop |author = Soderberg, T. and Poulter, C.D. |journal = Biochemistry |year = 2000 |volume = 39 |pages = 6546–6553 |pmid = 10828971 | doi = 10.1021/bi992775u | issue = 21}}</ref><ref>{{cite journal | title = ''Escherichia coli'' dimethylallyl diphosphate: tRNA dimethylallyltransferase: pre-steady-state kinetic studies |author = Moore, J.A., Mathis, J.R. and Poulter, C.D. |journal = Biochim. Biophys. Acta |year = 2000 |volume = 1479 |pages = 166–174 |pmid = 11004538 | doi = 10.1016/S0167-4838(00)00031-5 | issue = 1–2}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]<br />
<br />
: [[dimethylallyl diphosphate]] + [[Transfer RNA|tRNA]] <math>\rightleftharpoons</math> [[diphosphate]] + tRNA containing 6-dimethylallyladenosine<br />
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Formerly known as tRNA isopentenyltransferase (EC 2.5.1.8), but it is now known that dimethylallyl diphosphate, rather than [[isopentenyl diphosphate]], is the substrate.<br />
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== References ==<br />
{{reflist}}<br />
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== External links ==<br />
*{{MeshName|TRNA+dimethylallyltransferase}}<br />
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[[Category:EC 2.5.1]]</div>
193.198.16.211