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		<summary type="html">&lt;p&gt;18.62.0.15: /* Generalized (n,k) fork-join system */&lt;/p&gt;
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		<summary type="html">&lt;p&gt;18.62.16.245: /* Definition */&lt;/p&gt;
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&lt;div&gt;{{Infobox enzyme&lt;br /&gt;
| Name = NADH:ubiquinone reductase (Na&amp;lt;sup&amp;gt;+&amp;lt;/sup&amp;gt;-transporting)&lt;br /&gt;
| EC_number = 1.6.5.8&lt;br /&gt;
| CAS_number = &lt;br /&gt;
| IUBMB_EC_number = 1/6/5/8&lt;br /&gt;
| GO_code = &lt;br /&gt;
| image = &lt;br /&gt;
| width = &lt;br /&gt;
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}}&lt;br /&gt;
&#039;&#039;&#039;NADH:ubiquinone reductase (Na&amp;lt;sup&amp;gt;+&amp;lt;/sup&amp;gt;-transporting)&#039;&#039;&#039; ({{EC number|1.6.5.8}}, &#039;&#039;Na&amp;lt;sup&amp;gt;+&amp;lt;/sup&amp;gt;-translocating NADH-quinone reductase&#039;&#039;, &#039;&#039;(Na&amp;lt;sup&amp;gt;+&amp;lt;/sup&amp;gt;-NQR)&#039;&#039;) is an [[enzyme]] with system name &#039;&#039;NADH:ubiquinone oxidoreductase (Na&amp;lt;sup&amp;gt;+&amp;lt;/sup&amp;gt;-translocating)&#039;&#039;.&amp;lt;ref&amp;gt;{{cite journal | title = Cloning and sequencing of four structural genes for the Na&amp;lt;small&amp;gt;&amp;lt;sup&amp;gt;+&amp;lt;/sup&amp;gt;&amp;lt;/small&amp;gt;-translocating NADH-ubiquinone oxidoreductase of &amp;lt;em&amp;gt;Vibrio alginolyticus&amp;lt;/em&amp;gt; |author = Beattie, P., Tan, K., Bourne, R.M., Leach, D., Rich, P.R. and Ward, F.B. |journal = FEBS Lett. |year = 1994 |volume = 356 |pages = 333–338 |pmid = 7805867 |issue=2-3}}&amp;lt;/ref&amp;gt;&amp;lt;ref&amp;gt;{{cite journal | title = Identification of six subunits constituting Na&amp;lt;small&amp;gt;&amp;lt;sup&amp;gt;+&amp;lt;/sup&amp;gt;&amp;lt;/small&amp;gt;-translocating NADH-quinone reductase from the marine &amp;lt;em&amp;gt;Vibrio alginolyticus&amp;lt;/em&amp;gt; |author = Nakayama, Y., Hayashi, M. and Unemoto, T. |journal = FEBS Lett. |year = 1998 |volume = 422 |pages = 240–242 |pmid = 9490015 |issue=2}}&amp;lt;/ref&amp;gt;&amp;lt;ref&amp;gt;{{cite journal | title = Sodium-dependent steps in the redox reactions of the Na&amp;lt;small&amp;gt;&amp;lt;sup&amp;gt;+&amp;lt;/sup&amp;gt;&amp;lt;/small&amp;gt;-motive NADH:quinone oxidoreductase from &amp;lt;em&amp;gt;Vibrio harveyi&amp;lt;/em&amp;gt; |author = Bogachev, A.V., Bertsova, Y.V., Barquera, B. and Verkhovsky, M.I. |journal = Biochemistry |year = 2001 |volume = 40 |pages = 7318–7323 |pmid = 11401580 |issue=24}}&amp;lt;/ref&amp;gt;&amp;lt;ref&amp;gt;{{cite journal | title = Purification and characterization of the recombinant Na&amp;lt;small&amp;gt;&amp;lt;sup&amp;gt;+&amp;lt;/sup&amp;gt;&amp;lt;/small&amp;gt;-translocating NADH:quinone oxidoreductase from &amp;lt;em&amp;gt;Vibrio cholerae&amp;lt;/em&amp;gt; |author = Barquera, B., Hellwig, P., Zhou, W., Morgan, J.E., Hase, C.C., Gosink, K.K., Nilges, M., Bruesehoff, P.J., Roth, A., Lancaster, C.R. and Gennis, R.B. |journal = Biochemistry |year = 2002 |volume = 41 |pages = 3781–3789 |pmid = 11888296 |issue=11}}&amp;lt;/ref&amp;gt;&amp;lt;ref&amp;gt;{{cite journal | title = Mutagenesis study of the 2Fe-2S center and the FAD binding site of the Na&amp;lt;small&amp;gt;&amp;lt;sup&amp;gt;+&amp;lt;/sup&amp;gt;&amp;lt;/small&amp;gt;-translocating NADH:ubiquinone oxidoreductase from &amp;lt;em&amp;gt;Vibrio cholerae&amp;lt;/em&amp;gt; |author = Barquera, B., Nilges, M.J., Morgan, J.E., Ramirez-Silva, L., Zhou, W. and Gennis, R.B. |journal = Biochemistry |year = 2004 |volume = 43 |pages = 12322–12330 |pmid = 15379571 |doi=10.1021/bi048689y |issue=38}}&amp;lt;/ref&amp;gt; This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]&lt;br /&gt;
&lt;br /&gt;
: NADH + H&amp;lt;sup&amp;gt;+&amp;lt;/sup&amp;gt; + ubiquinone + n Na&amp;lt;sup&amp;gt;+&amp;lt;/sup&amp;gt;in &amp;lt;math&amp;gt;\rightleftharpoons&amp;lt;/math&amp;gt; NAD+ + ubiquinol + n Na&amp;lt;sup&amp;gt;+&amp;lt;/sup&amp;gt;out&lt;br /&gt;
&lt;br /&gt;
This enzyme is iron-sulfur flavoprotein.&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
{{reflist}}&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
* {{MeshName|NADH:ubiquinone+reductase+(Na+-transporting)}}&lt;br /&gt;
&lt;br /&gt;
[[Category:EC 1.6.5]]&lt;/div&gt;</summary>
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