Sholl analysis

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The iterative proportional fitting procedure (IPFP, also known as biproportional fitting in statistics, RAS algorithm[1] in economics and matrix raking or matrix scaling in computer science) is an iterative algorithm for estimating cell values of a contingency table such that the marginal totals remain fixed and the estimated table decomposes into an outer product.

First introduced by Deming and Stephan in 1940[2] (they proposed IPFP as an algorithm leading to a minimizer of the Pearson X-squared statistic, which it does not,[3] and even failed to prove convergence), it has seen various extensions and related research. A rigorous proof of convergence by means of differential geometry is due to Fienberg (1970).[4] He interpreted the family of contingency tables of constant crossproduct ratios as a particular (IJ − 1)-dimensional manifold of constant interaction and showed that the IPFP is a fixed-point iteration on that manifold. Nevertheless, he assumed strictly positive observations. Generalization to tables with zero entries is still considered a hard and only partly solved problem.

An exhaustive treatment of the algorithm and its mathematical foundations can be found in the book of Bishop et al. (1975).[5] The first general proof of convergence, built on non-trivial measure theoretic theorems and entropy minimization, is due to Csiszár (1975).[6] Relatively new results on convergence and error behavior have been published by Pukelsheim and Simeone (2009) .[7] They proved simple necessary and sufficient conditions for the convergence of the IPFP for arbitrary two-way tables (i.e. tables with zero entries) by analysing an L1-error function.

Other general algorithms can be modified to yield the same limit as the IPFP, for instance the Newton–Raphson method and the EM algorithm. In most cases, IPFP is preferred due to its computational speed, numerical stability and algebraic simplicity.

Algorithm 1 (classical IPFP)

Given a two-way (I × J)-table of counts (xij), where the cell values are assumed to be Poisson or multinomially distributed, we wish to estimate a decomposition m^ij=aibj for all i and j such that (m^ij) is the maximum likelihood estimate (MLE) of the expected values (mij) leaving the marginals xi+=jxij and x+j=ixij fixed. The assumption that the table factorizes in such a manner is known as the model of independence (I-model). Written in terms of a log-linear model, we can write this assumption as logmij=u+vi+wj+zij, where mij:=𝔼(xij), ivi=jwj=0 and the interaction term vanishes, that is zij=0 for all i and j.

Choose initial values m^ij(0):=1 (different choices of initial values may lead to changes in convergence behavior), and for η1 set

m^ij(2η1)=m^ij(2η2)xi+k=1Jm^ik(2η2)
m^ij(2η)=m^ij(2η1)x+jk=1Im^kj(2η1).

Notes:

  • Convergence does not depend on the actual distribution. Distributional assumptions are necessary for inferring that the limit (m^ij):=limη(m^ij(η)) is an MLE indeed.
  • IPFP can be manipulated to generate any positive marginals be replacing xi+ by the desired row marginal ui (analogously for the column marginals).
  • IPFP can be extended to fit the model of quasi-independence (Q-model), where mij=0 is known a priori for (i,j)S. Only the initial values have to be changed: Set m^ij(0)=0 if (i,j)S and 1 otherwise.

Algorithm 2 (factor estimation)

Assume the same setting as in the classical IPFP. Alternatively, we can estimate the row and column factors separately: Choose initial values b^j(0):=1, and for η1 set

a^i(η)=xi+jb^j(η1),
b^j(η)=x+jia^i(η)

Setting m^ij(2η)=a^i(η)b^j(η), the two variants of the algorithm are mathematically equivalent (can be seen by formal induction).

Notes:

a^i(η)=xi+jδijb^j(η1),
b^j(η)=x+jiδija^i(η)
m^ij(2η)=δija^i(η)b^j(η)

Obviously, the I-model is a particular case of the Q-model.

Algorithm 3 (RAS)

The Problem: Let M:=(mij(0))I×J be the initial matrix with nonnegative entries, uI a vector of specified row marginals (e.i. row sums) and vJ a vector of column marginals. We wish to compute a matrix M^=(m^ij)I×J similar to M with predefined marginals, meaning

a^i+=j=1na^ij=ui

and

a^+j=i=1ma^ij=vj

Define the diagonalization operator diag:kk×k, which produces a (diagonal) matrix with its input vector on the main diagonal and zero elsewhere. Then, for η0, set

M(2η+1)=diag(r(η+1))M(2η)
M(2η+2)=M(2η+1)diag(s(η+1))

where

riη+1=uijmij(2η)
sjη+1=vjimij(2η+1)

Finally, we obtain M^=limηM(η).

Discussion and comparison of the algorithms

Although RAS seems to be the solution of an entirely different problem, it is indeed identical to the classical IPFP. In practice, one would not implement actual matrix multiplication, since diagonal matrices are involved. Reducing the operations to the necessary ones, it can easily be seen that RAS does the same as IPFP. The vaguely demanded 'similarity' can be explained as follows: IPFP (and thus RAS) maintains the crossproduct ratios, e.i.

mij(0)mhk(0)mik(0)mhj(0)=mij(η)mhk(η)mik(η)mhj(η)η0 and ih,jk

since mij(η)=ai(η)bj(η).

This property is sometimes called structure conservation and directly leads to the geometrical interpretation of contingency tables and the proof of convergence in the seminal paper of Fienberg (1970).

Nevertheless, direct factor estimation (algorithm 2) is under all circumstances the best way to deal with IPF: Whereas classical IPFP needs

IJ(2+J)+IJ(2+I)=I2J+IJ2+4IJ

elementary operations in each iteration step (including a row and a column fitting step), factor estimation needs only

I(1+J)+J(1+I)=2IJ+I+J

operations being at least one order in magnitude faster than classical IPFP.

Existence and uniqueness of MLEs

Necessary and sufficient conditions for the existence and uniqueness of MLEs are complicated in the general case (see[8]), but sufficient conditions for 2-dimensional tables are simple:

  • the marginals of the observed table do not vanish (that is, xi+>0,x+j>0) and
  • the observed table is inseparable (e.i. the table does not permute to a block-diagonal shape).

If unique MLEs exist, IPFP exhibits linear convergence in the worst case (Fienberg 1970), but exponential convergence has also been observed (Pukelsheim and Simeone 2009). If a direct estimator (i.e. a closed form of (m^ij)) exists, IPFP converges after 2 iterations. If unique MLEs do not exist, IPFP converges toward the so-called extended MLEs by design (Haberman 1974), but convergence may be arbitrarily slow and often computationally infeasible.

If all observed values are strictly positive, existence and uniqueness of MLEs and therefore convergence is ensured.

Goodness of fit

Checking if the assumption of independence is adequate, one uses the Pearson X-squared statistic

X2=i,j(xijmij^)2mij^

or alternatively the likelihood-ratio test (G-test) statistic

G=2i,jxijlogxijm^ij.

Both statistics are asymptotically Xr2-distributed, where r=(I1)(J1) is the number of degrees of freedom. That is, if the p-values 1Xr2(X2) and 1Xr2(G) are not too small (> 0.05 for instance), there is no indication to discard the hypothesis of independence.

Interpretation

If the rows correspond to different values of property A, and the columns correspond to different values of property B, and the hypothesis of independence is not discarded, the properties A and B are considered independent.

Example

Consider a table of observations (taken from the entry on contingency tables):

right-handed left-handed TOTAL
male 43 9 52
female 44 4 48
TOTAL 87 13 100

For executing the classical IPFP, we first initialize the matrix with ones, leaving the marginals untouched:

right-handed left-handed TOTAL
male 1 1 52
female 1 1 48
TOTAL 87 13 100

Of course, the marginal sums do not correspond to the matrix anymore, but this is fixed in the next two iterations of IPFP. The first iteration deals with the row sums:

right-handed left-handed TOTAL
male 26 26 52
female 24 24 48
TOTAL 87 13 100

Note that, by definition, the row sums always constitute a perfect match after odd iterations, as do the column sums for even ones. The subsequent iteration updates the matrix column-wise:

right-handed left-handed TOTAL
male 45.24 6.76 52
female 41.76 6.24 48
TOTAL 87 13 100

Now, both row and column sums of the matrix match the given marginals again.

The p-value of this matrix approximates to p(X2)0.1824671, meaning: gender and left-handedness/right-handedness can be considered independent.

Notes

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    The data offered is for normal info purposes only and isn't supposed to be personalised investment or monetary advice. Motley Fool Singapore contributor Stanley Lim would not personal shares in any corporations talked about. Singapore private home costs increased by 1.eight% within the fourth quarter of 2012, up from 0.6% within the earlier quarter. Resale prices of government-built HDB residences which are usually bought by Singaporeans, elevated by 2.5%, quarter on quarter, the quickest acquire in five quarters. And industrial property, prices are actually double the levels of three years ago. No withholding tax in the event you sell your property. All your local information regarding vital HDB policies, condominium launches, land growth, commercial property and more

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    A vendor's stamp duty has been launched on industrial property for the primary time, at rates ranging from 5 per cent to 15 per cent. The Authorities might be trying to reassure the market that they aren't in opposition to foreigners and PRs investing in Singapore's property market. They imposed these measures because of extenuating components available in the market." The sale of new dual-key EC models will even be restricted to multi-generational households only. The models have two separate entrances, permitting grandparents, for example, to dwell separately. The vendor's stamp obligation takes effect right this moment and applies to industrial property and plots which might be offered inside three years of the date of buy. JLL named Best Performing Property Brand for second year running

    The data offered is for normal info purposes only and isn't supposed to be personalised investment or monetary advice. Motley Fool Singapore contributor Stanley Lim would not personal shares in any corporations talked about. Singapore private home costs increased by 1.eight% within the fourth quarter of 2012, up from 0.6% within the earlier quarter. Resale prices of government-built HDB residences which are usually bought by Singaporeans, elevated by 2.5%, quarter on quarter, the quickest acquire in five quarters. And industrial property, prices are actually double the levels of three years ago. No withholding tax in the event you sell your property. All your local information regarding vital HDB policies, condominium launches, land growth, commercial property and more

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  3. One of the biggest reasons investing in a Singapore new launch is an effective things is as a result of it is doable to be lent massive quantities of money at very low interest rates that you should utilize to purchase it. Then, if property values continue to go up, then you'll get a really high return on funding (ROI). Simply make sure you purchase one of the higher properties, reminiscent of the ones at Fernvale the Riverbank or any Singapore landed property Get Earnings by means of Renting

    In its statement, the singapore property listing - website link, government claimed that the majority citizens buying their first residence won't be hurt by the new measures. Some concessions can even be prolonged to chose teams of consumers, similar to married couples with a minimum of one Singaporean partner who are purchasing their second property so long as they intend to promote their first residential property. Lower the LTV limit on housing loans granted by monetary establishments regulated by MAS from 70% to 60% for property purchasers who are individuals with a number of outstanding housing loans on the time of the brand new housing purchase. Singapore Property Measures - 30 August 2010 The most popular seek for the number of bedrooms in Singapore is 4, followed by 2 and three. Lush Acres EC @ Sengkang

    Discover out more about real estate funding in the area, together with info on international funding incentives and property possession. Many Singaporeans have been investing in property across the causeway in recent years, attracted by comparatively low prices. However, those who need to exit their investments quickly are likely to face significant challenges when trying to sell their property – and could finally be stuck with a property they can't sell. Career improvement programmes, in-house valuation, auctions and administrative help, venture advertising and marketing, skilled talks and traisning are continuously planned for the sales associates to help them obtain better outcomes for his or her shoppers while at Knight Frank Singapore. No change Present Rules

    Extending the tax exemption would help. The exemption, which may be as a lot as $2 million per family, covers individuals who negotiate a principal reduction on their existing mortgage, sell their house short (i.e., for lower than the excellent loans), or take part in a foreclosure course of. An extension of theexemption would seem like a common-sense means to assist stabilize the housing market, but the political turmoil around the fiscal-cliff negotiations means widespread sense could not win out. Home Minority Chief Nancy Pelosi (D-Calif.) believes that the mortgage relief provision will be on the table during the grand-cut price talks, in response to communications director Nadeam Elshami. Buying or promoting of blue mild bulbs is unlawful.

    A vendor's stamp duty has been launched on industrial property for the primary time, at rates ranging from 5 per cent to 15 per cent. The Authorities might be trying to reassure the market that they aren't in opposition to foreigners and PRs investing in Singapore's property market. They imposed these measures because of extenuating components available in the market." The sale of new dual-key EC models will even be restricted to multi-generational households only. The models have two separate entrances, permitting grandparents, for example, to dwell separately. The vendor's stamp obligation takes effect right this moment and applies to industrial property and plots which might be offered inside three years of the date of buy. JLL named Best Performing Property Brand for second year running

    The data offered is for normal info purposes only and isn't supposed to be personalised investment or monetary advice. Motley Fool Singapore contributor Stanley Lim would not personal shares in any corporations talked about. Singapore private home costs increased by 1.eight% within the fourth quarter of 2012, up from 0.6% within the earlier quarter. Resale prices of government-built HDB residences which are usually bought by Singaporeans, elevated by 2.5%, quarter on quarter, the quickest acquire in five quarters. And industrial property, prices are actually double the levels of three years ago. No withholding tax in the event you sell your property. All your local information regarding vital HDB policies, condominium launches, land growth, commercial property and more

    There are various methods to go about discovering the precise property. Some local newspapers (together with the Straits Instances ) have categorised property sections and many local property brokers have websites. Now there are some specifics to consider when buying a 'new launch' rental. Intended use of the unit Every sale begins with 10 p.c low cost for finish of season sale; changes to 20 % discount storewide; follows by additional reduction of fiftyand ends with last discount of 70 % or extra. Typically there is even a warehouse sale or transferring out sale with huge mark-down of costs for stock clearance. Deborah Regulation from Expat Realtor shares her property market update, plus prime rental residences and houses at the moment available to lease Esparina EC @ Sengkang
  4. One of the biggest reasons investing in a Singapore new launch is an effective things is as a result of it is doable to be lent massive quantities of money at very low interest rates that you should utilize to purchase it. Then, if property values continue to go up, then you'll get a really high return on funding (ROI). Simply make sure you purchase one of the higher properties, reminiscent of the ones at Fernvale the Riverbank or any Singapore landed property Get Earnings by means of Renting

    In its statement, the singapore property listing - website link, government claimed that the majority citizens buying their first residence won't be hurt by the new measures. Some concessions can even be prolonged to chose teams of consumers, similar to married couples with a minimum of one Singaporean partner who are purchasing their second property so long as they intend to promote their first residential property. Lower the LTV limit on housing loans granted by monetary establishments regulated by MAS from 70% to 60% for property purchasers who are individuals with a number of outstanding housing loans on the time of the brand new housing purchase. Singapore Property Measures - 30 August 2010 The most popular seek for the number of bedrooms in Singapore is 4, followed by 2 and three. Lush Acres EC @ Sengkang

    Discover out more about real estate funding in the area, together with info on international funding incentives and property possession. Many Singaporeans have been investing in property across the causeway in recent years, attracted by comparatively low prices. However, those who need to exit their investments quickly are likely to face significant challenges when trying to sell their property – and could finally be stuck with a property they can't sell. Career improvement programmes, in-house valuation, auctions and administrative help, venture advertising and marketing, skilled talks and traisning are continuously planned for the sales associates to help them obtain better outcomes for his or her shoppers while at Knight Frank Singapore. No change Present Rules

    Extending the tax exemption would help. The exemption, which may be as a lot as $2 million per family, covers individuals who negotiate a principal reduction on their existing mortgage, sell their house short (i.e., for lower than the excellent loans), or take part in a foreclosure course of. An extension of theexemption would seem like a common-sense means to assist stabilize the housing market, but the political turmoil around the fiscal-cliff negotiations means widespread sense could not win out. Home Minority Chief Nancy Pelosi (D-Calif.) believes that the mortgage relief provision will be on the table during the grand-cut price talks, in response to communications director Nadeam Elshami. Buying or promoting of blue mild bulbs is unlawful.

    A vendor's stamp duty has been launched on industrial property for the primary time, at rates ranging from 5 per cent to 15 per cent. The Authorities might be trying to reassure the market that they aren't in opposition to foreigners and PRs investing in Singapore's property market. They imposed these measures because of extenuating components available in the market." The sale of new dual-key EC models will even be restricted to multi-generational households only. The models have two separate entrances, permitting grandparents, for example, to dwell separately. The vendor's stamp obligation takes effect right this moment and applies to industrial property and plots which might be offered inside three years of the date of buy. JLL named Best Performing Property Brand for second year running

    The data offered is for normal info purposes only and isn't supposed to be personalised investment or monetary advice. Motley Fool Singapore contributor Stanley Lim would not personal shares in any corporations talked about. Singapore private home costs increased by 1.eight% within the fourth quarter of 2012, up from 0.6% within the earlier quarter. Resale prices of government-built HDB residences which are usually bought by Singaporeans, elevated by 2.5%, quarter on quarter, the quickest acquire in five quarters. And industrial property, prices are actually double the levels of three years ago. No withholding tax in the event you sell your property. All your local information regarding vital HDB policies, condominium launches, land growth, commercial property and more

    There are various methods to go about discovering the precise property. Some local newspapers (together with the Straits Instances ) have categorised property sections and many local property brokers have websites. Now there are some specifics to consider when buying a 'new launch' rental. Intended use of the unit Every sale begins with 10 p.c low cost for finish of season sale; changes to 20 % discount storewide; follows by additional reduction of fiftyand ends with last discount of 70 % or extra. Typically there is even a warehouse sale or transferring out sale with huge mark-down of costs for stock clearance. Deborah Regulation from Expat Realtor shares her property market update, plus prime rental residences and houses at the moment available to lease Esparina EC @ Sengkang
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  6. One of the biggest reasons investing in a Singapore new launch is an effective things is as a result of it is doable to be lent massive quantities of money at very low interest rates that you should utilize to purchase it. Then, if property values continue to go up, then you'll get a really high return on funding (ROI). Simply make sure you purchase one of the higher properties, reminiscent of the ones at Fernvale the Riverbank or any Singapore landed property Get Earnings by means of Renting

    In its statement, the singapore property listing - website link, government claimed that the majority citizens buying their first residence won't be hurt by the new measures. Some concessions can even be prolonged to chose teams of consumers, similar to married couples with a minimum of one Singaporean partner who are purchasing their second property so long as they intend to promote their first residential property. Lower the LTV limit on housing loans granted by monetary establishments regulated by MAS from 70% to 60% for property purchasers who are individuals with a number of outstanding housing loans on the time of the brand new housing purchase. Singapore Property Measures - 30 August 2010 The most popular seek for the number of bedrooms in Singapore is 4, followed by 2 and three. Lush Acres EC @ Sengkang

    Discover out more about real estate funding in the area, together with info on international funding incentives and property possession. Many Singaporeans have been investing in property across the causeway in recent years, attracted by comparatively low prices. However, those who need to exit their investments quickly are likely to face significant challenges when trying to sell their property – and could finally be stuck with a property they can't sell. Career improvement programmes, in-house valuation, auctions and administrative help, venture advertising and marketing, skilled talks and traisning are continuously planned for the sales associates to help them obtain better outcomes for his or her shoppers while at Knight Frank Singapore. No change Present Rules

    Extending the tax exemption would help. The exemption, which may be as a lot as $2 million per family, covers individuals who negotiate a principal reduction on their existing mortgage, sell their house short (i.e., for lower than the excellent loans), or take part in a foreclosure course of. An extension of theexemption would seem like a common-sense means to assist stabilize the housing market, but the political turmoil around the fiscal-cliff negotiations means widespread sense could not win out. Home Minority Chief Nancy Pelosi (D-Calif.) believes that the mortgage relief provision will be on the table during the grand-cut price talks, in response to communications director Nadeam Elshami. Buying or promoting of blue mild bulbs is unlawful.

    A vendor's stamp duty has been launched on industrial property for the primary time, at rates ranging from 5 per cent to 15 per cent. The Authorities might be trying to reassure the market that they aren't in opposition to foreigners and PRs investing in Singapore's property market. They imposed these measures because of extenuating components available in the market." The sale of new dual-key EC models will even be restricted to multi-generational households only. The models have two separate entrances, permitting grandparents, for example, to dwell separately. The vendor's stamp obligation takes effect right this moment and applies to industrial property and plots which might be offered inside three years of the date of buy. JLL named Best Performing Property Brand for second year running

    The data offered is for normal info purposes only and isn't supposed to be personalised investment or monetary advice. Motley Fool Singapore contributor Stanley Lim would not personal shares in any corporations talked about. Singapore private home costs increased by 1.eight% within the fourth quarter of 2012, up from 0.6% within the earlier quarter. Resale prices of government-built HDB residences which are usually bought by Singaporeans, elevated by 2.5%, quarter on quarter, the quickest acquire in five quarters. And industrial property, prices are actually double the levels of three years ago. No withholding tax in the event you sell your property. All your local information regarding vital HDB policies, condominium launches, land growth, commercial property and more

    There are various methods to go about discovering the precise property. Some local newspapers (together with the Straits Instances ) have categorised property sections and many local property brokers have websites. Now there are some specifics to consider when buying a 'new launch' rental. Intended use of the unit Every sale begins with 10 p.c low cost for finish of season sale; changes to 20 % discount storewide; follows by additional reduction of fiftyand ends with last discount of 70 % or extra. Typically there is even a warehouse sale or transferring out sale with huge mark-down of costs for stock clearance. Deborah Regulation from Expat Realtor shares her property market update, plus prime rental residences and houses at the moment available to lease Esparina EC @ Sengkang
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  8. 20 year-old Real Estate Agent Rusty from Saint-Paul, has hobbies and interests which includes monopoly, property developers in singapore and poker. Will soon undertake a contiki trip that may include going to the Lower Valley of the Omo.

    My blog: http://www.primaboinca.com/view_profile.php?userid=5889534