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| Name = 3-Isopropylmalate dehydrogenase
| EC_number = 1.1.1.85
| CAS_number = 9030-97-1
| IUBMB_EC_number = 1/1/1/85
| GO_code = 0003862
| image =
| width =
| caption =
}}
'''3-Isopropylmalate dehydrogenase'''  ({{EC number|1.1.1.85}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]s<ref name="pmid14087358">{{cite journal | author = Burns RO, Umbarger HE, Gross, SR | title = The biosynthesis of leucine. III. The conversion of α-hydroxy-β-carboxyisocaproate to α-ketoisocaproate. | journal = Biochemistry | volume = 2 | issue = | pages = 1053–8 | year = 1963 | pmid = 14087358 | doi = 10.1021/bi00905a024| url = }}</ref><ref name="pmid14269331">{{cite journal | author = Calvo JM, Stevens CM, Kalyanpur MG, Umbarger HE | title = The Absolute Configuration of α-carboxyisocaproic Acid (3-Isopropylmalic Acid), an Intermediate in Leucine Biosynthesis | journal = Biochemistry | volume = 3 | issue = | pages = 2024–7 |date=December 1964 | pmid = 14269331 | doi = 10.1021/bi00900a043}}</ref><ref name="pmid4889950">{{cite journal | author = Parsons SJ, Burns RO | title = Purification and Properties of ''β''-Isopropylmalate Dehydrogenase | journal = J. Biol. Chem. | volume = 244 | issue = 3 | pages = 996–1003 |date=February 1969 | pmid = 4889950 | doi =  }}</ref><ref name="pmid10683439">{{cite journal | author = Németh A, Svingor A, Pócsik M, Dobó J, Magyar C, Szilágyi A, Gál P, Závodszky P | title = Mirror image mutations reveal the significance of an intersubunit ion cluster in the stability of 3-isopropylmalate dehydrogenase | journal = FEBS Lett. | volume = 468 | issue = 1 | pages = 48–52 |date=February 2000 | pmid = 10683439 | doi = 10.1016/S0014-5793(00)01190-X}}</ref>
:[[isopropylmalate|(2R,3S)-3-isopropylmalate]] + [[Nicotinamide adenine dinucleotide|NAD<sup>+</sup>]] <math>\rightleftharpoons</math> 4-methyl-2-oxopentanoate + [[Carbon dioxide|CO<sub>2</sub>]] + [[Nicotinamide adenine dinucleotide|NADH]]
:(2R,3S)-3-isopropylmalate + NAD<sup>+</sup> <math>\rightleftharpoons</math> (2S)-2-isopropyl-3-oxosuccinate + H<sup>+</sup> + NADH
:(2S)-2-isopropyl-3-oxosuccinate + H<sup>+</sup> <math>\rightleftharpoons</math> 4-methyl-2-oxopentanoate + CO<sub>2</sub>
 
== References ==
{{Reflist}}
 
[[Category:EC 1.1.1]]
[[Category:NADPH-dependent enzymes]]
[[Category:Enzymes of known structure]]
 
 
{{1.1.1-enzyme-stub}}

Latest revision as of 12:18, 5 April 2014

Hindi news media are getting famous among all the people in India. The presentation of news is so lucid and transparent people today of our society are strongly concentrating on this media. Utilizing their own home people can get all the updates of their society with prior answers. The journalists who work on news media are totally dedicated for the contemporary society. They risk their life and get all of the updates of news reports so that people of our country can get every piece of information in the time frame and in the way. Be it Bihar news or Patna news, individuals are only interest in latest news and happenings of our society.

The ringing of the doorbell interrupts Henry's evening ritual: watching TV, dissipating the ugg news of disasters and wars from all over the world. Only a door-to-door salesman would enjoy the gall to bother some guy at the moment. And true to character, he -- she? -- isn't content to ring once. There it goes again.

Though for the reason that started as practical footwear for Australian sheepherders, today they are increasingly becoming an integral part each celebrity's wardrobe. Of special interest are Womens' ugg boots that come in different options and myriad range of colours to suit different tastes, outfits and occasions. Here are a few popular options, which may get mix and match to your outfit.

DO And not simply settle for cheap boots. Yes, do they protect you the bad. But invest a little extra for better sizes and heights. Take note of especially where did they fit your legs.

You know those fabulous studded suede ankle boots I mentioned earlier; well, I need also mentioned that I'm 27-years-old. Would I recommend those same boots to my 56-year-old mother? Unequivocally no! However, a nice pair of taupe slouchy suede flat ankle boots with a sweet little tie detail in the back, just as the Horkey style from Aldo Shoes; yes, absolutely. These types of much more age appropriate and comfortable without straying from vast majority. Age appropriate is key, here, ladies. There are many some of shoes I have passed over because not a soul over this of 25 with a school degree probably full-time job should even consider being seen within them.

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