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In [[statistics]], when performing [[multiple comparisons]], the term '''false positive ratio''', also known as the '''false alarm ratio''', usually refers to the probability of falsely rejecting the [[null hypothesis]] for a particular [[hypothesis test|test]].


The false positive '''rate''' (or "false alarm rate") usually refers to the '''expectancy''' of the false positive '''ratio'''.


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== Definition ==
 
Suppose we have ''m'' null hypotheses, denoted by: ''H''<sub>1</sub>,&nbsp;''H''<sub>2</sub>,&nbsp;...,&nbsp;''H''<sub>''m''</sub>.<br />
Using a [[Statistical hypothesis testing|statistical test]], each hypothesis is declared significant/non-significant.<br />
Summing the test results over <math>H_i</math> will give us the following table and related random variables:
 
{|class="wikitable"
! |
! Null hypothesis is True
! Alternative hypothesis is True
! | Total
|- align="center"
! | Declared significant
| <math>V</math>
| <math>S</math>
| <math>R</math>
|- align="center"
! | Declared non-significant
| <math>U</math>
| <math>T</math>
| <math>m - R</math>
|- align="center"
! Total
| <math>m_0</math>
| <math>m - m_0</math>
| <math>m</math>
|}
 
* <math>m_0</math> is the number of true [[null hypothesis|null hypotheses]], an unknown parameter
* <math>m - m_0</math> is the number of true [[alternative hypothesis|alternative hypotheses]]
* <math>V</math> is the number of [[Type I and type II errors|false positives (Type I error)]]
* <math>S</math> is the number of [[Type I and type II errors|true positives]]
* <math>T</math> is the number of [[Type I and type II errors|false negatives (Type II error)]]
* <math>U</math> is the number of [[Type I and type II errors|true negatives]]
* <math>R</math> is the number of rejected null hypotheses. It is an observable [[random variable]], while <math>S</math>, <math>T</math>, <math>U</math>, and <math>V</math> are unobservable [[random variable]]s.
 
The level of significance that is used to test each hypothesys is set based on the form of inference ([[Familywise error rate#Simultaneous inference vs. selective inference|simultaneous inference vs. selective inference]]) and its supporting criteria (for example [[Familywise error rate|FWER]] or [[False discovery rate|FDR]]), that were pre-determined by the researcher.
 
When performing [[multiple comparisons]] in a [[statistics|statistical]] framework such as above, the '''false positive ratio''' (also known as the '''false alarm ratio''', as opposed to false positive '''rate''' / false alarm '''rate''' ) usually refers to the probability of falsely rejecting the [[null hypothesis]] for a particular [[hypothesis test|test]]. Using the terminology suggested here, it is simply <math>V/m_0</math>.
 
Since ''V'' is a random variable and ''m_0'' is a constant (<math> V \leq m_0 </math>), the false positive '''ratio''' is also a random variable, ranging between 0-1.
<br />
The '''false positive rate''' (or "false alarm rate") usually refers to the '''expectancy of the false positive ratio''', expressed by <math>E(V/m_0)</math>.
 
It is worth noticing that the two definitions ("false positive ratio" / "false positive rate") are somewhat interchangeable. For example, in the referenced article<ref name=Burke.at.all1988>{{cite journal | last1 = Burke | first1= Donald | first2= John | last2= Brundage | last3= Redfield | first3= Robert | year = 1988 | title = Measurement of the False Positive Rate in a Screening Program for Human Immunodeficiency Virus Infections | journal = [[The New England Journal of Medicine]] | volume = 319 | pages = 961–964 | url = http://www.nejm.org/doi/pdf/10.1056/NEJM198810133191501 | doi=10.1056/NEJM198810133191501}}</ref> <math>V/m_0</math> serves as the false positive "rate" rather than as its "ratio".
 
== The difference between "false positive rate", "type I error rate" and other close terms ==
{{original research section|date=February 2013}}
While the false positive rate is mathematically equal to the [[type I error]] rate, it is viewed as a separate term for the following reasons:{{citation needed|date=February 2013}}
 
* The [[type I error]] rate is often associated with the '''a-prior''' setting of the [[significance level]] by the researcher: the significance level represents an acceptable error rate '''considering that all null hypotheses are true''' (the "global null" hypothesis). the choice of a significance level may thus be somewhat arbitrary (i.e. setting 10% (0.1), 5% (0.05), 1% (0.01) etc.)
 
: As opposed to that, the false positive rate is associated with a '''post-prior''' result, which is the expected number of false positives divided by the total number of hypotheses under the '''real''' combination of true and non-true null hypotheses (disregarding the "global null" hypothesis). Since the false positive rate is a parameter that is not controlled by the researcher, it cannot be identified with the significance level.
 
* Moreover, false positive rate is a term usually used regarding a medical test or diagnostic device (i.e. "the false positive rate of a certain diagnostic device is 1%"), while type I error is a term associated with statistical tests, where the meaning of the word "positive" is not as clear (i.e. "the type I error of a test is 1%").
 
The false positive rate should also not be confused with the [[familywise error rate]], which is defined as <math> \mathrm{FWER} = \Pr(V \ge 1)\,</math>. As the number of tests grows, the familywise error rate usually converges to 1 while the false positive rate remains fixed.
 
Lastly, it is important to note the profound difference between the false positive rate and the [[false discovery rate]]: while the first is defined as <math>E(V/m_0)</math>, the second is defined as <math>E(V/R)</math>.
 
== References ==
 
<references />
 
[[Category:Multiple comparisons]]
[[Category:Statistical tests]]
[[Category:Analysis of variance]]

Revision as of 12:17, 24 January 2014

In statistics, when performing multiple comparisons, the term false positive ratio, also known as the false alarm ratio, usually refers to the probability of falsely rejecting the null hypothesis for a particular test.

The false positive rate (or "false alarm rate") usually refers to the expectancy of the false positive ratio.

Definition

Suppose we have m null hypotheses, denoted by: H1H2, ..., Hm.
Using a statistical test, each hypothesis is declared significant/non-significant.
Summing the test results over Hi will give us the following table and related random variables:

Null hypothesis is True Alternative hypothesis is True Total
Declared significant V S R
Declared non-significant U T mR
Total m0 mm0 m

The level of significance that is used to test each hypothesys is set based on the form of inference (simultaneous inference vs. selective inference) and its supporting criteria (for example FWER or FDR), that were pre-determined by the researcher.

When performing multiple comparisons in a statistical framework such as above, the false positive ratio (also known as the false alarm ratio, as opposed to false positive rate / false alarm rate ) usually refers to the probability of falsely rejecting the null hypothesis for a particular test. Using the terminology suggested here, it is simply V/m0.

Since V is a random variable and m_0 is a constant (Vm0), the false positive ratio is also a random variable, ranging between 0-1.
The false positive rate (or "false alarm rate") usually refers to the expectancy of the false positive ratio, expressed by E(V/m0).

It is worth noticing that the two definitions ("false positive ratio" / "false positive rate") are somewhat interchangeable. For example, in the referenced article[1] V/m0 serves as the false positive "rate" rather than as its "ratio".

The difference between "false positive rate", "type I error rate" and other close terms

Template:Original research section While the false positive rate is mathematically equal to the type I error rate, it is viewed as a separate term for the following reasons:Potter or Ceramic Artist Truman Bedell from Rexton, has interests which include ceramics, best property developers in singapore developers in singapore and scrabble. Was especially enthused after visiting Alejandro de Humboldt National Park.

  • The type I error rate is often associated with the a-prior setting of the significance level by the researcher: the significance level represents an acceptable error rate considering that all null hypotheses are true (the "global null" hypothesis). the choice of a significance level may thus be somewhat arbitrary (i.e. setting 10% (0.1), 5% (0.05), 1% (0.01) etc.)
As opposed to that, the false positive rate is associated with a post-prior result, which is the expected number of false positives divided by the total number of hypotheses under the real combination of true and non-true null hypotheses (disregarding the "global null" hypothesis). Since the false positive rate is a parameter that is not controlled by the researcher, it cannot be identified with the significance level.
  • Moreover, false positive rate is a term usually used regarding a medical test or diagnostic device (i.e. "the false positive rate of a certain diagnostic device is 1%"), while type I error is a term associated with statistical tests, where the meaning of the word "positive" is not as clear (i.e. "the type I error of a test is 1%").

The false positive rate should also not be confused with the familywise error rate, which is defined as FWER=Pr(V1). As the number of tests grows, the familywise error rate usually converges to 1 while the false positive rate remains fixed.

Lastly, it is important to note the profound difference between the false positive rate and the false discovery rate: while the first is defined as E(V/m0), the second is defined as E(V/R).

References

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