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| | In [[pharmacokinetics]], the '''rate of infusion''' (or '''dosing rate''') refers not just to the rate at which a drug is administered, but the desired rate at which a drug ''should'' be administered to achieve a steady state of a fixed dose which has been demonstrated to be therapeutically effective. |
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| | Abbreviations include K<sub>in</sub>, <ref name="urlCp vs time - iv infusion">{{cite web |url=http://www.chm.davidson.edu/erstevens/iv%20inf%20Cp%20v%20t/iv%20inf%20Cp%20v%20t.html |title=Cp vs time - iv infusion |format= |work= |accessdate=}}</ref> K<sub>0</sub>, <ref name="urlChapter 15.2 - Continuous IV Infusion - Steady State">{{cite web |url=http://www.boomer.org/c/p3/c15/c1502.html |title=Chapter 15.2 - Continuous IV Infusion - Steady State |format= |work= |accessdate=}}</ref> or R<sub>0</sub>. |
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| | It can be calculated as the [[steady-state concentration]] in the plasma multiplied by the [[Clearance (medicine)|clearance]]: |
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| | <math>\textstyle K_{in} = C_{ss} \cdot CL</math> |
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| | ==References== |
| | {{reflist}} |
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| | {{pharmacology-stub}} |
| | {{Pharmacology}} |
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| | [[Category:Pharmacology]] |
Revision as of 19:00, 27 January 2014
In pharmacokinetics, the rate of infusion (or dosing rate) refers not just to the rate at which a drug is administered, but the desired rate at which a drug should be administered to achieve a steady state of a fixed dose which has been demonstrated to be therapeutically effective.
Abbreviations include Kin, [1] K0, [2] or R0.
It can be calculated as the steady-state concentration in the plasma multiplied by the clearance:
References
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Template:Pharmacology-stub
Template:Pharmacology