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{{enzyme
| Name = 3-oxoadipyl-CoA thiolase
| EC_number = 2.3.1.174
| CAS_number =
| IUBMB_EC_number = 2/3/1/174
| GO_code =
| image =
| width =  
| caption =  
}}
In [[enzymology]], a '''3-oxoadipyl-CoA thiolase''' ({{EC number|2.3.1.174}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:succinyl-CoA + acetyl-CoA <math>\rightleftharpoons</math> CoA + 3-oxoadipyl-CoA
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[succinyl-CoA]] and [[acetyl-CoA]], whereas its two [[product (chemistry)|products]] are [[coenzyme A|CoA]] and [[3-oxoadipyl-CoA]].
 
This enzyme belongs to the family of [[transferase]]s, specifically those [[acyltransferase]]s transferring groups other than aminoacyl groups. The systematic name of this enzyme class is '''succinyl-CoA:acetyl-CoA C-succinyltransferase'''. This enzyme participates in [[benzoate degradation via hydroxylation]].
 
3-Oxoadipyl-CoA thiolase belongs to the [[thiolase]] family of enzymes.
 
==References==
{{reflist|1}}
* {{cite journal | author = Kaschabek SR, Kuhn B, Muller D, Schmidt E, Reineke W | date = 2002 | title = Degradation of Aromatics and Chloroaromatics by Pseudomonas sp. Strain B13: Purification and Characterization of 3-Oxoadipate:Succinyl-Coenzyme A (CoA) Transferase and 3-Oxoadipyl-CoA Thiolase | journal = J. Bacteriol. | volume = 184 | pages = 207&ndash;15  | pmid = 11741862 | doi = 10.1128/JB.184.1.207-215.2002 | issue = 1 | pmc = 134768 }}
* {{cite journal | author = Gobel M, Kassel-Cati K, Schmidt E, Reineke W | date = 2002 | title = Degradation of Aromatics and Chloroaromatics by Pseudomonas sp. Strain B13: Cloning, Characterization, and Analysis of Sequences Encoding 3-Oxoadipate:Succinyl-Coenzyme A (CoA) Transferase and 3-Oxoadipyl-CoA Thiolase | journal = J. Bacteriol| volume = 184 | pages = 216&ndash;23  | pmid = 11741863 | doi = 10.1128/JB.184.1.216-223.2002 | issue = 1 | pmc = 134769 }}
 
{{transferase-stub}}
 
[[Category:EC 2.3.1]]
[[Category:Enzymes of unknown structure]]

Latest revision as of 21:40, 17 March 2013

Template:Enzyme In enzymology, a 3-oxoadipyl-CoA thiolase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

succinyl-CoA + acetyl-CoA CoA + 3-oxoadipyl-CoA

Thus, the two substrates of this enzyme are succinyl-CoA and acetyl-CoA, whereas its two products are CoA and 3-oxoadipyl-CoA.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is succinyl-CoA:acetyl-CoA C-succinyltransferase. This enzyme participates in benzoate degradation via hydroxylation.

3-Oxoadipyl-CoA thiolase belongs to the thiolase family of enzymes.

References

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Template:Transferase-stub