1-alkyl-2-acetylglycerol O-acyltransferase

Template:Enzyme In enzymology, a 2-ethylmalate synthase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + H₂O + 2-oxobutanoate $\rightleftharpoons$ (R)-2-ethylmalate + CoA

The 3 substrates of this enzyme are acetyl-CoA, H₂O, and 2-oxobutanoate, whereas its two products are (R)-2-ethylmalate and CoA.

This enzyme belongs to the family of transferases, specifically those acyltransferases that convert acyl groups into alkyl groups on transfer. The systematic name of this enzyme class is acetyl-CoA:2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming). Other names in common use include (R)-2-ethylmalate 2-oxobutanoyl-lyase (CoA-acetylating), 2-ethylmalate-3-hydroxybutanedioate synthase, propylmalate synthase, and propylmalic synthase. This enzyme participates in pyruvate metabolism.

References

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