(R)-2-haloacid dehalogenase

Template:Enzyme In enzymology, a 2-dehydro-3-deoxy-6-phosphogalactonate aldolase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

2-dehydro-3-deoxy-D-galactonate 6-phosphate $\rightleftharpoons$ pyruvate + D-glyceraldehyde 3-phosphate

Hence, this enzyme has one substrate, 2-dehydro-3-deoxy-D-galactonate 6-phosphate, and two products, pyruvate and D-glyceraldehyde 3-phosphate.

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2-dehydro-3-deoxy-D-galactonate-6-phosphate D-glyceraldehyde-3-phosphate-lyase (pyruvate-forming). Other names in common use include 6-phospho-2-keto-3-deoxygalactonate aldolase, phospho-2-keto-3-deoxygalactonate aldolase, 2-keto-3-deoxy-6-phosphogalactonic aldolase, phospho-2-keto-3-deoxygalactonic aldolase, 2-keto-3-deoxy-6-phosphogalactonic acid aldolase, (KDPGal)aldolase, 2-dehydro-3-deoxy-D-galactonate-6-phosphate, and D-glyceraldehyde-3-phosphate-lyase. This enzyme participates in galactose metabolism.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link and Template:PDB link.

References

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