Adleman–Pomerance–Rumely primality test: Difference between revisions
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The '''cellular Potts model''' is a [[lattice model (physics)|lattice]]-based computational modeling method to simulate the collective behavior of cellular structures. Other names for the CPM are '''extended large-q Potts model''' and '''Glazier and Graner model'''. First developed by [[James Glazier]] and [[Francois Graner]] in 1992 as an extension of large-q [[Potts model]] simulations of coarsening in metallic grains and soap froths, it has now been used to simulate [[foam]], [[biological tissues]], fluid flow and [[reaction-advection-diffusion-equations]]. In the CPM a generalized "cell" is a [[simply-connected]] [[subset|domain]] of [[pixels]] with the same ''cell id'' (formerly ''[[spin (physics)|spin]]''). A generalized cell may be a single [[soap bubble]], an entire [[biological cell]], part of a biological cell, or even a region of fluid. | |||
The CPM is evolved by updating the cell lattice one pixel at a time based on a set of probabilistic rules. In this sense, the CPM can be thought of as a generalized [[cellular automaton]] (''CA''). Although it also closely resembles certain [[Monte Carlo methods]], such as the large-q [[Potts model]], many subtle differences separate the CPM from Potts models and standard spin-based Monte Carlo schemes. | |||
The primary rule base has three components: | |||
# rules for selecting putative lattice updates | |||
# a ''[[Hamiltonian (quantum mechanics)|Hamiltonian]]'' or ''effective energy'' function that is used for calculating the [[probability]] of accepting lattice updates. | |||
# additional rules not included in 1. or 2.. | |||
The CPM can also be thought of as an ''[[agent based]]'' method in which cell agents evolve, interact via behaviors such as [[cell adhesion|adhesion]], [[cell signalling|signalling]], volume and surface area control, [[chemotaxis]] and [[cell proliferation|proliferation]]. Over time, the CPM has evolved from a specific model to a general framework with many extensions and even related methods that are entirely or partially off-lattice.{{citation needed|date=December 2010}} | |||
The central component of the CPM is the definition of the Hamiltonian. The Hamiltonian is determined by the configuration of the cell lattice and perhaps other sub-lattices containing information such as the concentrations of chemicals. The original CPM Hamiltonian included adhesion energies, and volume and surface area constraints. We present a simple example for illustration: | |||
<math> | |||
\begin{align} | |||
H = & \sum_{ i, j \text{ neighbors}} J\left(\tau(\sigma(i)), \tau(\sigma( j))\right) \left(1 - \delta(\sigma( i), \sigma( j))\right) \\ | |||
+ & \sum_{ i} \lambda_\text{volume}[V(\sigma( i)) - V_\text{target}(\sigma( i))]^2\\ | |||
+ & \sum_{ i} \lambda_\text{surface}[S(\sigma(i)) - S_\text{target}(\sigma( i))]^2 .\\ | |||
\end{align} | |||
</math> | |||
Where for cell σ, λ<sub>volume</sub> is the volume constraint, V<sub>target</sub> is the target volume, and for neighbouring lattice sites i and j, J is the boundary coefficient between two cells (σ,σ') of given types τ(σ),τ(σ'), and the boundary energy coefficients are symmetric: J[τ(σ),τ(σ')]=J[τ(σ'),τ(σ)], and the Kronecker delta is δ<sub>(x,y)</sub>={1,x=y; 0,x≠y}. | |||
Many extensions to the original CPM Hamiltonian control cell behaviors including [[chemotaxis]], elongation and [[haptotaxis]]. | |||
==References== | |||
*{{cite journal |first=François |last=Graner |first2=James A. |last2=Glazier |year=1992 |title=Simulation of Biological Cell Sorting Using a Two-Dimensional Extended Potts Model |journal=[[Physical Review Letters|Phys. Rev. Lett.]] |volume=69 |issue=13 |pages=2013–2016 |doi=10.1103/PhysRevLett.69.2013 }} | |||
*{{cite journal |first=Nan |last=Chen |first2=James A. |last2=Glazier |first3=Jesus A. |last3=Izaguirre |first4=Mark S. |last4=Alber |year=2007 |title=A parallel implementation of the Cellular Potts Model for simulation of cell-based morphogenesis |journal=Computer Physics Communications |volume=176 |issue=11–12 |pages=670–681 |doi=10.1016/j.cpc.2007.03.007 }} | |||
==External links== | |||
*[http://biocomplexity.indiana.edu/jglazier/ James Glazier] (professional website) | |||
*[[CompuCell3D]], a CPM simulation environment: [http://sourceforge.net/projects/compucell/ Sourceforge] | |||
*[https://simtk.org/home/compucell3d/ SimTK] | |||
*[http://www.nd.edu/~lcls/compucell/linux.htm Notre Dame development site] | |||
*[http://panmental.de/ALifeXIflag Artificial Life model of multicellular morphogenesis with autonomously generated gradients for positional information using the Cellular Potts model] | |||
{{DEFAULTSORT:Cellular Potts Model}} | |||
[[Category:Statistical mechanics]] | |||
[[Category:Lattice models]] | |||
[[Category:Stochastic models]] |
Revision as of 05:28, 30 December 2013
The cellular Potts model is a lattice-based computational modeling method to simulate the collective behavior of cellular structures. Other names for the CPM are extended large-q Potts model and Glazier and Graner model. First developed by James Glazier and Francois Graner in 1992 as an extension of large-q Potts model simulations of coarsening in metallic grains and soap froths, it has now been used to simulate foam, biological tissues, fluid flow and reaction-advection-diffusion-equations. In the CPM a generalized "cell" is a simply-connected domain of pixels with the same cell id (formerly spin). A generalized cell may be a single soap bubble, an entire biological cell, part of a biological cell, or even a region of fluid.
The CPM is evolved by updating the cell lattice one pixel at a time based on a set of probabilistic rules. In this sense, the CPM can be thought of as a generalized cellular automaton (CA). Although it also closely resembles certain Monte Carlo methods, such as the large-q Potts model, many subtle differences separate the CPM from Potts models and standard spin-based Monte Carlo schemes.
The primary rule base has three components:
- rules for selecting putative lattice updates
- a Hamiltonian or effective energy function that is used for calculating the probability of accepting lattice updates.
- additional rules not included in 1. or 2..
The CPM can also be thought of as an agent based method in which cell agents evolve, interact via behaviors such as adhesion, signalling, volume and surface area control, chemotaxis and proliferation. Over time, the CPM has evolved from a specific model to a general framework with many extensions and even related methods that are entirely or partially off-lattice.Potter or Ceramic Artist Truman Bedell from Rexton, has interests which include ceramics, best property developers in singapore developers in singapore and scrabble. Was especially enthused after visiting Alejandro de Humboldt National Park.
The central component of the CPM is the definition of the Hamiltonian. The Hamiltonian is determined by the configuration of the cell lattice and perhaps other sub-lattices containing information such as the concentrations of chemicals. The original CPM Hamiltonian included adhesion energies, and volume and surface area constraints. We present a simple example for illustration:
Where for cell σ, λvolume is the volume constraint, Vtarget is the target volume, and for neighbouring lattice sites i and j, J is the boundary coefficient between two cells (σ,σ') of given types τ(σ),τ(σ'), and the boundary energy coefficients are symmetric: J[τ(σ),τ(σ')]=J[τ(σ'),τ(σ)], and the Kronecker delta is δ(x,y)={1,x=y; 0,x≠y}.
Many extensions to the original CPM Hamiltonian control cell behaviors including chemotaxis, elongation and haptotaxis.
References
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The data offered is for normal info purposes only and isn't supposed to be personalised investment or monetary advice. Motley Fool Singapore contributor Stanley Lim would not personal shares in any corporations talked about. Singapore private home costs increased by 1.eight% within the fourth quarter of 2012, up from 0.6% within the earlier quarter. Resale prices of government-built HDB residences which are usually bought by Singaporeans, elevated by 2.5%, quarter on quarter, the quickest acquire in five quarters. And industrial property, prices are actually double the levels of three years ago. No withholding tax in the event you sell your property. All your local information regarding vital HDB policies, condominium launches, land growth, commercial property and more
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In its statement, the singapore property listing - website link, government claimed that the majority citizens buying their first residence won't be hurt by the new measures. Some concessions can even be prolonged to chose teams of consumers, similar to married couples with a minimum of one Singaporean partner who are purchasing their second property so long as they intend to promote their first residential property. Lower the LTV limit on housing loans granted by monetary establishments regulated by MAS from 70% to 60% for property purchasers who are individuals with a number of outstanding housing loans on the time of the brand new housing purchase. Singapore Property Measures - 30 August 2010 The most popular seek for the number of bedrooms in Singapore is 4, followed by 2 and three. Lush Acres EC @ Sengkang
Discover out more about real estate funding in the area, together with info on international funding incentives and property possession. Many Singaporeans have been investing in property across the causeway in recent years, attracted by comparatively low prices. However, those who need to exit their investments quickly are likely to face significant challenges when trying to sell their property – and could finally be stuck with a property they can't sell. Career improvement programmes, in-house valuation, auctions and administrative help, venture advertising and marketing, skilled talks and traisning are continuously planned for the sales associates to help them obtain better outcomes for his or her shoppers while at Knight Frank Singapore. No change Present Rules
Extending the tax exemption would help. The exemption, which may be as a lot as $2 million per family, covers individuals who negotiate a principal reduction on their existing mortgage, sell their house short (i.e., for lower than the excellent loans), or take part in a foreclosure course of. An extension of theexemption would seem like a common-sense means to assist stabilize the housing market, but the political turmoil around the fiscal-cliff negotiations means widespread sense could not win out. Home Minority Chief Nancy Pelosi (D-Calif.) believes that the mortgage relief provision will be on the table during the grand-cut price talks, in response to communications director Nadeam Elshami. Buying or promoting of blue mild bulbs is unlawful.
A vendor's stamp duty has been launched on industrial property for the primary time, at rates ranging from 5 per cent to 15 per cent. The Authorities might be trying to reassure the market that they aren't in opposition to foreigners and PRs investing in Singapore's property market. They imposed these measures because of extenuating components available in the market." The sale of new dual-key EC models will even be restricted to multi-generational households only. The models have two separate entrances, permitting grandparents, for example, to dwell separately. The vendor's stamp obligation takes effect right this moment and applies to industrial property and plots which might be offered inside three years of the date of buy. JLL named Best Performing Property Brand for second year running
The data offered is for normal info purposes only and isn't supposed to be personalised investment or monetary advice. Motley Fool Singapore contributor Stanley Lim would not personal shares in any corporations talked about. Singapore private home costs increased by 1.eight% within the fourth quarter of 2012, up from 0.6% within the earlier quarter. Resale prices of government-built HDB residences which are usually bought by Singaporeans, elevated by 2.5%, quarter on quarter, the quickest acquire in five quarters. And industrial property, prices are actually double the levels of three years ago. No withholding tax in the event you sell your property. All your local information regarding vital HDB policies, condominium launches, land growth, commercial property and more
There are various methods to go about discovering the precise property. Some local newspapers (together with the Straits Instances ) have categorised property sections and many local property brokers have websites. Now there are some specifics to consider when buying a 'new launch' rental. Intended use of the unit Every sale begins with 10 p.c low cost for finish of season sale; changes to 20 % discount storewide; follows by additional reduction of fiftyand ends with last discount of 70 % or extra. Typically there is even a warehouse sale or transferring out sale with huge mark-down of costs for stock clearance. Deborah Regulation from Expat Realtor shares her property market update, plus prime rental residences and houses at the moment available to lease Esparina EC @ Sengkang
External links
- James Glazier (professional website)
- CompuCell3D, a CPM simulation environment: Sourceforge
- SimTK
- Notre Dame development site
- Artificial Life model of multicellular morphogenesis with autonomously generated gradients for positional information using the Cellular Potts model