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| {{enzyme
| | Alyson is the name people use to contact me and I think it seems fairly great when you say it. He is an info officer. I've always cherished residing in Alaska. To perform lacross is some thing he would by no means give up.<br><br>My web site; free online tarot card readings ([http://bigpolis.com/blogs/post/6503 my explanation]) |
| | Name = progesterone 5-alpha-reductase
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| | EC_number = 1.3.1.30
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| | CAS_number = 72412-84-1
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| | IUBMB_EC_number = 1/3/1/30
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| | GO_code = 0050213
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| In [[enzymology]], a '''progesterone 5alpha-reductase''' ({{EC number|1.3.1.30}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
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| :5alpha-pregnan-3,20-dione + NADP<sup>+</sup> <math>\rightleftharpoons</math> progesterone + NADPH + H<sup>+</sup>
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| Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[5alpha-pregnan-3,20-dione]] and [[nicotinamide adenine dinucleotide phosphate|NADP<sup>+</sup>]], whereas its 3 [[product (chemistry)|products]] are [[progesterone]], [[nicotinamide adenine dinucleotide phosphate|NADPH]], and [[hydrogen ion|H<sup>+</sup>]].
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| This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is '''5alpha-pregnan-3,20-dione:NADP+ 5-oxidoreductase'''. Other names in common use include '''steroid 5-alpha-reductase''', and '''Delta4-steroid 5alpha-reductase (progesterone)'''. This enzyme participates in [[c21-steroid hormone metabolism]].
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| ==References==
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| {{reflist|1}}
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| * {{cite journal | author = Cheng YJ, Karavolas HJ | date = 1975 | title = Subcellular distribution and properties of progesterone (delta4-steroid) 5alpha-reductase in rat medial basal hypothalamus | journal = J. Biol. Chem. | volume = 250 | pages = 7997–8003 | pmid = 240847 | issue = 20 }}
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| * {{cite journal | author = Cheng YJ, Karavolas HJ | date = 1975 | title = Properties and subcellular distribution of delta4-steroid (progesterone) 5alpha-reductase in rat anterior pituitary | journal = Steroids. | volume = 26 | pages = 57–71 | pmid = 1166484 | doi = 10.1016/0039-128X(75)90006-9 | issue = 1 }}
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| {{1.3-enzyme-stub}}
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| [[Category:EC 1.3.1]]
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| [[Category:NADPH-dependent enzymes]]
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| [[Category:Enzymes of unknown structure]]
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Latest revision as of 01:49, 5 April 2014
Alyson is the name people use to contact me and I think it seems fairly great when you say it. He is an info officer. I've always cherished residing in Alaska. To perform lacross is some thing he would by no means give up.
My web site; free online tarot card readings (my explanation)