Retardation factor: Difference between revisions

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en>DMacks
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en>DMacks
that's what it is called, so that's what we call it. Undid revision 641924205 by 86.173.154.216 (talk)
 
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The '''Certain Safety Factor''' is the ratio of the [[lethal dose]] to 1% of population to the [[Effective dose (pharmacology)|effective dose]] to 99% of the population (LD1/ED99). This is a better safety index than the [[Median lethal dose|LD<sub>50</sub>]] for materials that have both desirable and undesirable effects, because it factors in the ends of the spectrum where doses may be necessary to produce a response in one person but can, at the same dose, be lethal in another.
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<math>\mbox{Certain safety factor} = \frac{\mathrm{LD}_{1}}{\mathrm{ED}_{99}}</math>
 
==See also==
* [[Therapeutic index]]
* [[Effective dose (pharmacology)|Effective dose]]
* [[IC50|IC<sub>50</sub>]]
* {{LD50}}
* [[EC50|EC<sub>50</sub>]]
* [[Toxicology]]
 
==References==
http://www.courses.vcu.edu/ptxed/m2/faqs_damaj.htm
 
[[Category:Pharmacology]]
[[Category:Toxicology]]
 
{{pharma-stub}}
{{med-toxic-stub}}

Latest revision as of 22:55, 10 January 2015

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