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{{Infobox enzyme
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| Name = Minus-end-directed kinesin ATPase
| EC_number = 3.6.4.5
| CAS_number =
| IUBMB_EC_number = 3/6/4/5
| GO_code =
| image =
| width =
| caption =
}}
'''Minus-end-directed kinesin ATPase''' ({{EC number|3.6.4.5}}) is an [[enzyme]] with system name ''kinesin ATP phosphohydrolase (minus-end-directed)''.<ref>{{cite journal | title = Reversal in the direction of movement of a molecular motor |author = Henningsen, U. and Schliwa, M. |journal = Nature |date = 1997 |volume = 389 |pages = 93-96 |pmid = 9288974 |doi=10.1038/38022}}</ref><ref>{{cite journal | title = Expression of a minus-end-directed motor protein induces Sh9 cells to form axon-like processes with uniform microtubule polarity orientation |author = Sharp, D.J., Kuriyama, R., Essner, R. and Baas, P.W. |journal = J. Cell Sci. |date = 1997 |volume = 110 |pages = 2373-2380 |pmid = 9410876}}</ref><ref>{{cite journal | title = Direction determination in the minus-end-directed kinesin motor ncd |author = Sablin, E.P.,  CASe, R.B., Dai, S.C., Hart, C.L., Ruby, A., Vale, R.D. and Fletterick, R.J. |journal = Nature |date = 1998 |volume = 395 |pages = 813-816 |pmid = 99010841}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]
 
: ATP + H<sub>2</sub>O <math>\rightleftharpoons</math> ADP + [[phosphate]]
 
This enzyme catalyses movement towards the minus end of [[microtubule]]s.
 
== References ==
{{reflist}}
 
== See also ==
* [[Kinesin]]
 
== External links ==
* {{MeshName|Minus-end-directed+kinesin+ATPase}}
 
[[Category:EC 3.6.4]]

Latest revision as of 07:02, 29 December 2014

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