Phosphoribulokinase: Difference between revisions

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{{enzyme
| Name = pyridoxal kinase
| EC_number = 2.7.1.35
| CAS_number = 9026-42-0
| IUBMB_EC_number = 2/7/1/35
| GO_code = 0008478
| image =
| width =
| caption =
}}
In [[enzymology]], a '''pyridoxal kinase''' ({{EC number|2.7.1.35}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:ATP + pyridoxal <math>\rightleftharpoons</math> ADP + pyridoxal 5'-phosphate
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[adenosine triphosphate|ATP]] and [[pyridoxal]], whereas its two [[product (chemistry)|products]] are [[adenosine diphosphate|ADP]] and [[pyridoxal 5'-phosphate]].
 
This enzyme belongs to the family of [[transferase]]s, specifically those transferring phosphorus-containing groups ([[phosphotransferase]]s) with an alcohol group as acceptor. The systematic name of this enzyme class is '''ATP:pyridoxal 5'-phosphotransferase'''. Other names in common use include '''pyridoxal kinase (phosphorylating)''', '''pyridoxal 5-phosphate-kinase''', '''pyridoxal phosphokinase''', and '''pyridoxine kinase'''. This enzyme participates in [[vitamin B6|vitamin B<sub>6</sub> metabolism]]. 
 
==Structural studies==
 
As of late 2007, 15 [[tertiary structure|structures]] have been solved for this class of enzymes, with [[Protein Data Bank|PDB]] accession codes {{PDB link|1LHP}}, {{PDB link|1LHR}}, {{PDB link|1RFT}}, {{PDB link|1RFU}}, {{PDB link|1RFV}}, {{PDB link|1TD2}}, {{PDB link|1VI9}}, {{PDB link|1YGJ}}, {{PDB link|1YGK}}, {{PDB link|1YHJ}}, {{PDB link|2AJP}}, {{PDB link|2DDM}}, {{PDB link|2DDO}}, {{PDB link|2DDW}}, and {{PDB link|2F7K}}.
 
==References==
{{reflist|1}}
* {{cite journal | author = McCormick DB, Gregory ME and Snell EE | date = 1961 | title = Pyridoxal phosphokinases. I. Assay, distribution, purification, and properties | journal = J. Biol. Chem| volume = 236 | pages = 2076&ndash;2084 | pmid=13773826}}
* {{cite journal | author = Trufanov AF and Krisanova JA | date = 6 | title = Biosynthesis of pyridoxal phosphate by liver sections of rat in vitro | journal = Byull. Eksp. Biol. Med. | volume = 22 | pages = 40&ndash;43 }}
 
{{enzyme-stub}}
 
[[Category:EC 2.7.1]]
[[Category:Enzymes of known structure]]

Latest revision as of 10:59, 3 November 2013

Template:Enzyme In enzymology, a pyridoxal kinase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

ATP + pyridoxal ADP + pyridoxal 5'-phosphate

Thus, the two substrates of this enzyme are ATP and pyridoxal, whereas its two products are ADP and pyridoxal 5'-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:pyridoxal 5'-phosphotransferase. Other names in common use include pyridoxal kinase (phosphorylating), pyridoxal 5-phosphate-kinase, pyridoxal phosphokinase, and pyridoxine kinase. This enzyme participates in vitamin B6 metabolism.

Structural studies

As of late 2007, 15 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, and Template:PDB link.

References

43 year old Petroleum Engineer Harry from Deep River, usually spends time with hobbies and interests like renting movies, property developers in singapore new condominium and vehicle racing. Constantly enjoys going to destinations like Camino Real de Tierra Adentro.

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    A vendor's stamp duty has been launched on industrial property for the primary time, at rates ranging from 5 per cent to 15 per cent. The Authorities might be trying to reassure the market that they aren't in opposition to foreigners and PRs investing in Singapore's property market. They imposed these measures because of extenuating components available in the market." The sale of new dual-key EC models will even be restricted to multi-generational households only. The models have two separate entrances, permitting grandparents, for example, to dwell separately. The vendor's stamp obligation takes effect right this moment and applies to industrial property and plots which might be offered inside three years of the date of buy. JLL named Best Performing Property Brand for second year running

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Template:Enzyme-stub