https://en.formulasearchengine.com/index.php?action=history&feed=atom&title=Stable_process
Stable process - Revision history
2026-05-17T04:31:22Z
Revision history for this page on the wiki
MediaWiki 1.43.0-wmf.28
https://en.formulasearchengine.com/index.php?title=Stable_process&diff=28806&oldid=prev
en>Michael Hardy at 03:09, 3 March 2013
2013-03-03T03:09:28Z
<p></p>
<p><b>New page</b></p><div>{{Infobox enzyme<br />
| Name = Arsenite methyltransferase<br />
| EC_number = 2.1.1.137<br />
| CAS_number = 167140-41-2<br />
| IUBMB_EC_number = 2/1/1/137<br />
| GO_code = <br />
| image = <br />
| width = <br />
| caption =<br />
}}<br />
'''Arsenite methyltransferase''' ({{EC number|2.1.1.137}}, ''S-adenosyl-L-methionine:arsenic(III) methyltransferase'', ''S-adenosyl-L-methionine:methylarsonite As-methyltransferase'', ''methylarsonite methyltransferase'') is an [[enzyme]] with system name ''S-adenosyl-L-methionine:arsenite As-methyltransferase''.<ref>{{cite journal | title = Enzymatic reduction of arsenic compounds in mammalian systems: the rate-limiting enzyme of rabbit liver arsenic biotransformation is MMA(V) reductase |author = Zakharyan, R.A. and [[H. Vasken Aposhian|Aposhian, H.V.]] |journal = Chem. Res. Toxicol. |date = 1999 |volume = 12 |pages = 1278–1283 |pmid = 10604879 | doi = 10.1021/tx9901231 | issue = 12}}</ref><ref>{{cite journal | title = Enzymatic methylation of arsenic compounds. VII. Monomethylarsonous acid (MMAIII) is the substrate for MMA methyltransferase of rabbit liver and human hepatocytes |author = Zakharyan, R.A., Ayala-Fierro, F., Cullen, W.R., Carter, D.M. and Aposhian, H.V. |journal = Toxicol. Appl. Pharmacol. |date = 1999 |volume = 158 |pages = 9–15 |pmid = 10387927 | doi = 10.1006/taap.1999.8687 | issue = 1}}</ref><ref>{{cite journal | title = Enzymatic methylation of arsenic compounds. III. The marmoset and tamarin, but not the rhesus, monkeys are deficient in methyltransferases that methylate inorganic arsenic |author = Zakharyan, R.A., Wildfang, E. and Aposhian, H.V. |journal = Toxicol. Appl. Pharmacol. |date = 1996 |volume = 140 |pages = 77–84 |pmid = 8806872 | doi = 10.1006/taap.1996.0199 | issue = 1}}</ref><ref>{{cite journal | title = Enzymatic methylation of arsenic compounds: assay, partial purification, and properties of arsenite methyltransferase and monomethylarsonic acid methyltransferase of rabbit liver |author = Zakharyan, R.A., Wu, Y., Bogdan, G.M. and Aposhian, H.V. |journal = Chem. Res. Toxicol. |date = 1995 |volume = 8 |pages = 1029–1038 |pmid = 8605285 | doi = 10.1021/tx00050a006 | issue = 8}}</ref><ref>{{cite journal | title = A novel <em>S</em>-adenosyl-<small>L</small>-methionine:arsenic(III) methyltransferase from rat liver cytosol |author = Lin, S., Shi, Q., Nix, F.B., Styblo, M., Beck, M.A., Herbin-Davis, K.M., Hall, L.L., Simeonsson, J.B. and Thomas, D.J. |journal = J. Biol. Chem. |date = 2002 |volume = 277 |pages = 10795–10803 |pmid = 11790780 | doi = 10.1074/jbc.M110246200 | issue = 13}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]<br />
<br />
: (1) [[S-adenosyl-L-methionine]] + [[arsenite]] <math>\rightleftharpoons</math> [[S-adenosyl-L-homocysteine]] + [[methylarsonate]]<br />
: (2) S-adenosyl-L-methionine + methylarsonite <math>\rightleftharpoons</math> S-adenosyl-L-homocysteine + [[dimethylarsinate]]<br />
<br />
An enzyme of the biotransformation pathway that forms dimethylarsinate from inorganic arsenite and arsenate. <br />
<br />
== References ==<br />
{{reflist}}<br />
<br />
== External links ==<br />
* {{MeshName|Arsenite+methyltransferase}}<br />
<br />
[[Category:EC 2.1.1]]</div>
en>Michael Hardy