https://en.formulasearchengine.com/index.php?action=history&feed=atom&title=Ratio_estimator Ratio estimator - Revision history 2026-05-03T23:19:01Z Revision history for this page on the wiki MediaWiki 1.43.0-wmf.28 https://en.formulasearchengine.com/index.php?title=Ratio_estimator&diff=28769&oldid=prev 129.97.59.156 at 19:30, 29 October 2013 2013-10-29T19:30:47Z <p></p> <p><b>New page</b></p><div>{{Infobox enzyme<br /> | Name = Pyrimidine oxygenase<br /> | EC_number = 1.14.99.46<br /> | CAS_number = <br /> | IUBMB_EC_number = 1/14/99/46<br /> | GO_code = <br /> | image = <br /> | width = <br /> | caption =<br /> }}<br /> &#039;&#039;&#039;Pyrimidine oxygenase&#039;&#039;&#039; ({{EC number|1.14.99.46}}, &#039;&#039;RutA&#039;&#039;) is an [[enzyme]] with system name &#039;&#039;uracil,FMNH&lt;sub&gt;2&lt;/sub&gt;:oxygen oxidoreductase (uracil hydroxylating, ring-opening) &#039;&#039;.&lt;ref&gt;{{cite journal | title = Catalysis of a flavoenzyme-mediated amide hydrolysis |author = Mukherjee, T., Zhang, Y., Abdelwahed, S., Ealick, S.E. and Begley, T.P. |journal = J. Am. Chem. Soc. |year = 2010 |volume = 132 |pages = 5550–5551 |pmid = 20369853 |doi=10.1021/ja9107676 |issue=16 |pmc=2873085}}&lt;/ref&gt;&lt;ref&gt;{{cite journal | title = The Rut pathway for pyrimidine degradation: novel chemistry and toxicity problems |author = Kim, K.S., Pelton, J.G., Inwood, W.B., Andersen, U., Kustu, S. and Wemmer, D.E. |journal = J. Bacteriol. |year = 2010 |volume = 192 |pages = 4089–4102 |pmid = 20400551 |doi=10.1128/JB.00201-10 |issue=16 |pmc=2916427}}&lt;/ref&gt; This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]<br /> <br /> : (1) [[uracil]] + FMNH&lt;sub&gt;2&lt;/sub&gt; + O&lt;sub&gt;2&lt;/sub&gt; &lt;math&gt;\rightleftharpoons&lt;/math&gt; (Z)-3-ureidoacrylate peracid + FMN<br /> : (2) [[thymine]] + FMNH&lt;sub&gt;2&lt;/sub&gt; + O&lt;sub&gt;2&lt;/sub&gt; &lt;math&gt;\rightleftharpoons&lt;/math&gt; (Z)-2-methylureidoacrylate peracid + FMN<br /> <br /> In vitro the product (Z)-3-ureidoacrylate peracid is spontaneously reduced to [[ureidoacrylate]].<br /> <br /> == References ==<br /> {{reflist}}<br /> <br /> == External links ==<br /> * {{MeshName|Pyrimidine+oxygenase}}<br /> <br /> [[Category:EC 1.14.99]]</div> 129.97.59.156