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{{Infobox enzyme
| Name = Tropine acyltransferase
| EC_number = 2.3.1.185
| CAS_number = 138440-79-6, 162535-29-7
| IUBMB_EC_number = 2/3/1/185
| GO_code =
| image =
| width =
| caption =
}}
'''Tropine acyltransferase''' ({{EC number|2.3.1.185}}, ''tropine:acyl-CoA transferase'', ''acetyl-CoA:tropan-3-ol acyltransferase'', ''tropine acetyltransferase'', ''tropine tigloyltransferase'', ''TAT'') is an [[enzyme]] with system name ''acyl-CoA:tropine O-acyltransferase''.<ref>{{cite journal | title = The formation of 3α- and 3β-acetoxytropanes by ''Datura stramonium'' transformed root cultures involves two acetyl-CoA-dependent acyltransferases |author = Robins, R.J., Bachmann, P., Robinson, T., Rhodes, M.J. and Yamada, Y. |journal = FEBS Lett. |year = 1991 |volume = 292 |pages = 293–297 |pmid = 1959620}}</ref><ref>{{cite journal | title = Esterification reactions in the biosynthesis of tropane alkaloids in transformed root cultures |author = Robins, R.J., Bachmann,P., Peerless, A.C.J. and Rabot, S. |journal = Plant Cell, Tissue Organ Cult. |year = 1994 |volume = 38 |pages = 241–247 |pmid = }}</ref><ref>{{cite journal | title = Specificities of the enzymes of ''N''-alkyltropane biosynthesis in ''Brugmansia'' and ''Datura'' |author = Boswell, H.D., Dräger, B., McLauchlan, W.R., Portsteffen, A., Robins, D.J., Robins, R.J. and Walton, N.J. |journal = Phytochemistry |year = 1999 |volume = 52 |pages = 871–878 |pmid = 10626376 |doi=10.1016/S0031-9422(99)00293-9}}</ref><ref>{{cite journal | title = Functional genomic analysis of alkaloid biosynthesis in ''Hyoscyamus niger'' reveals a cytochrome ''P''<sub>450</sub> involved in littorine rearrangement |author = Li, R., Reed, D.W., Liu, E., Nowak, J., Pelcher, L.E., Page, J.E. and Covello, P.S. |journal = Chem. Biol. |year = 2006 |volume = 13 |pages = 513–520 |pmid = 16720272 |doi=10.1016/j.chembiol.2006.03.005}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: [[acyl-CoA]] + [[tropine]] <math>\rightleftharpoons</math> CoA + O-acyltropine

This enzyme exhibits absolute specificity for the endo/3alpha configuration found in tropine as [[pseudotropine]].

== References ==
{{reflist}}

== External links ==
* {{MeshName|Tropine+acyltransferase}}

[[Category:EC 2.3.1]]

Radial basis function kernel - Revision history

en>Qwertyus: /* References */ multicolumn