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<p><span class="autocomment">Geometric properties of quotient space: </span> bloat</p> <p><b>New page</b></p><div>{{Infobox enzyme<br /> | Name = Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase<br /> | EC_number = 3.6.1.53<br /> | CAS_number = <br /> | IUBMB_EC_number = 3/6/1/53<br /> | GO_code = <br /> | image = <br /> | width = <br /> | caption =<br /> }}<br /> &#039;&#039;&#039;Mn&lt;sup&gt;2+&lt;/sup&gt;-dependent ADP-ribose/CDP-alcohol diphosphatase&#039;&#039;&#039; ({{EC number|3.6.1.53}}, &#039;&#039;Mn2+-dependent ADP-ribose/CDP-alcohol pyrophosphatase&#039;&#039;, &#039;&#039;ADPRibase-Mn&#039;&#039;) is an [[enzyme]] with system name &#039;&#039;CDP-choline phosphohydrolase&#039;&#039;.&lt;ref&gt;{{cite journal | title = Rat liver nucleoside diphosphosugar or diphosphoalcohol pyrophosphatases different from nucleotide pyrophosphatase or phosphodiesterase I: substrate specificities of Mg&lt;sup&gt;2+&lt;/sup&gt;-and/or Mn&lt;sup&gt;2+&lt;/sup&gt;-dependent hydrolases acting on ADP-ribose |author = Canales, J., Pinto, R.M., Costas, M.J., Hern&amp;aacute;ndez, M.T., Mir&amp;oacute;, A., Bernet, D., Fern&amp;aacute;ndez, A. and Cameselle, J.C. |journal = Biochim. Biophys. Acta |year = 1995 |volume = 1246 |pages = 167–177 |pmid = 7819284}}&lt;/ref&gt;&lt;ref&gt;{{cite journal | title = Mn&lt;sup&gt;2+&lt;/sup&gt;-dependent ADP-ribose/CDP-alcohol pyrophosphatase: a novel metallophosphoesterase family preferentially expressed in rodent immune cells |author = Canales, J., Fern&amp;aacute;ndez, A., Ribeiro, J.M., Cabezas, A., Rodrigues, J.R., Cameselle, J.C. and Costas, M.J. |journal = Biochem. J. |year = 2008 |volume = 413 |pages = 103–113 |pmid = 18352857}}&lt;/ref&gt; This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]<br /> <br /> : (1) [[CDP-choline]] + H&lt;sub&gt;2&lt;/sub&gt;O &lt;math&gt;\rightleftharpoons&lt;/math&gt; CMP + [[phosphocholine]]<br /> : (2) [[ADP-ribose]] + H&lt;sub&gt;2&lt;/sub&gt;O &lt;math&gt;\rightleftharpoons&lt;/math&gt; AMP + D-ribose 5-phosphate<br /> <br /> This enzyme requires Mn&lt;sup&gt;2+&lt;/sup&gt;, which cannot be replaced by Mg&lt;sup&gt;2+&lt;/sup&gt;.<br /> <br /> == References ==<br /> {{reflist}}<br /> <br /> == External links ==<br /> * {{MeshName|Mn2+-dependent+ADP-ribose/CDP-alcohol+diphosphatase}}<br /> <br /> {{DEFAULTSORT:Mn2+-dependent ADP-ribose CDP-alcohol diphosphatase}}<br /> [[Category:EC 3.6.1]]</div>

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