https://en.formulasearchengine.com/index.php?action=history&feed=atom&title=Biomaterial_Surface_Modifications 2026-05-20T02:02:28Z Revision history for this page on the wiki MediaWiki 1.43.0-wmf.28 https://en.formulasearchengine.com/index.php?title=Biomaterial_Surface_Modifications&diff=29450&oldid=prev 2013-10-31T18:59:32Z

<p>Disambiguated: <a href="/index.php?title=Permeability&amp;action=edit&amp;redlink=1" class="new" title="Permeability (page does not exist)">permeability</a> → <a href="/wiki/Permeation" title="Permeation">Permeation</a></p> <p><b>New page</b></p><div>{{Infobox enzyme<br /> | Name = N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase<br /> | EC_number = 3.5.1.103<br /> | CAS_number = <br /> | IUBMB_EC_number = 3/5/1/103<br /> | GO_code = <br /> | image = <br /> | width = <br /> | caption =<br /> }}<br /> &#039;&#039;&#039;N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase&#039;&#039;&#039; ({{EC number|3.5.1.103}}, &#039;&#039;MshB&#039;&#039;) is an [[enzyme]] with system name &#039;&#039;1-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol acetylhydrolase&#039;&#039;.&lt;ref&gt;{{cite journal | title = Inactivation of &lt;em&gt;mshB&lt;/em&gt;, a key gene in the mycothiol biosynthesis pathway in &lt;em&gt;Mycobacterium smegmatis&lt;/em&gt; |author = Rawat, M., Kovacevic, S., Billman-Jacobe, H. and Av-Gay, Y. |journal = Microbiology |date = 2003 |volume = 149 |pages = 1341-1349 |pmid = 12724395}}&lt;/ref&gt;&lt;ref&gt;{{cite journal | title = &lt;em&gt;N&lt;/em&gt;-Acetyl-1-&lt;small&gt;D&lt;/small&gt;-&lt;em&gt;myo&lt;/em&gt;-inosityl-2-amino-2-deoxy-&amp;alpha;-&lt;small&gt;D&lt;/small&gt;-glucopyranoside deacetylase (MshB) is a key enzyme in mycothiol biosynthesis |author = Newton, G.L., Av-Gay, Y. and Fahey, R.C. |journal = J. Bacteriol. |date = 2000 |volume = 182 |pages = 6958-6963 |pmid = 11092856}}&lt;/ref&gt;&lt;ref&gt;{{cite journal | title = The crystal structure of 1-&lt;small&gt;D&lt;/small&gt;-&lt;em&gt;myo&lt;/em&gt;-inosityl 2-acetamido-2-deoxy-&amp;alpha;-&lt;small&gt;D&lt;/small&gt;-glucopyranoside deacetylase (MshB) from &lt;em&gt;Mycobacterium tuberculosis&lt;/em&gt; reveals a zinc hydrolase with a lactate dehydrogenase fold |author = Maynes, J.T., Garen, C., Cherney, M.M., Newton, G., Arad, D., Av-Gay, Y., Fahey, R.C. and James, M.N. |journal = J. Biol. Chem. |date = 2003 |volume = 278 |pages = 47166-47170 |pmid = 12958317}}&lt;/ref&gt; This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]<br /> <br /> : 1-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + H&lt;sub&gt;2&lt;/sub&gt;O &lt;math&gt;\rightleftharpoons&lt;/math&gt; 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol + [[acetate]]<br /> <br /> This enzyme mediates the rate limiting step in the [[mycothiol]] biosynthesis pathway.<br /> <br /> == References ==<br /> {{reflist}}<br /> <br /> == External links ==<br /> * {{MeshName|N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside+deacetylase}}<br /> <br /> [[Category:Hydrolases acting on nonpeptide C-N bonds]]<br /> [[Category:EC 3.5.1]]</div>

en>SteinbDJ