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{{enzyme
| Name = aspartate racemase
| EC_number = 5.1.1.13
| CAS_number = 37237-56-2
| IUBMB_EC_number = 5/1/1/13
| GO_code = 0047689
| image =
| width =
| caption =
}}
In [[enzymology]], an '''aspartate racemase''' ({{EC number|5.1.1.13}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:L-aspartate <math>\rightleftharpoons</math> D-aspartate

Hence, this enzyme has one [[substrate (biochemistry)|substrate]], [[aspartic acid|L-aspartate]], and one [[product (chemistry)|product]], [[aspartic acid|D-aspartate]].

This enzyme belongs to the family of [[isomerase]]s, specifically those [[racemase]]s and [[epimerase]]s acting on [[amino acid]]s and derivatives. The systematic name of this enzyme class is '''aspartate racemase'''. Other names in common use include '''D-aspartate racemase''', and '''McyF'''. This enzyme participates in [[alanine]] and [[aspartate]] metabolism.

==Structural studies==

As of late 2007, 3 [[tertiary structure|structures]] have been solved for this class of enzymes, with [[Protein Data Bank|PDB]] accession codes {{PDB link|1IU9}}, {{PDB link|1JFL}}, and {{PDB link|2DX7}}.

==References==
{{reflist|1}}
* {{cite journal | author = Lamont HC, Staudenbauer WL, Strominger JL | date = 1972 | title = Partial purification and characterization of an aspartate racemase from Streptococcus faecalis | journal = J. Biol. Chem. | volume = 247 | pages = 5103–6 | pmid = 4626916 | issue = 16 }}
* {{cite journal | author = Yamauchi T, Choi SY, Okada H, Yohda M, Kumagai H, Esaki N, Soda K | date = 1992 | title = Properties of aspartate racemase, a pyridoxal 5'-phosphate-independent amino acid racemase | journal = J. Biol. Chem. | volume = 267 | pages = 18361–4 | pmid = 1526977 | issue = 26 }}
* {{cite journal | author = Liu L, Iwata K, Kita A, Kawarabayasi Y, Yohda M, Miki K | date = 2002 | title = Crystal structure of aspartate racemase from Pyrococcus horikoshii OT3 and its implications for molecular mechanism of PLP-independent racemization | journal = J. Mol. Biol. | volume = 319 | pages = 479–89 | pmid = 12051922 | doi = 10.1016/S0022-2836(02)00296-6 | issue = 2 }}
* {{cite journal | author = H, Borner T, Schwecke T | date = 2003 | title = The mcyF gene of the microcystin biosynthetic gene cluster from Microcystis aeruginosa encodes an aspartate racemase | journal = Biochem. J. | volume = 373 | pages = 909–16 | pmid = 12713441 | doi = 10.1042/BJ20030396 | issue = Pt 3 | pmc = 1223527 }}
* {{cite journal | author = Yamashita T, Ashiuchi M, Ohnishi K, Kato S, Nagata S, Misono H | date = 2004 | title = Molecular identification of monomeric aspartate racemase from Bifidobacterium bifidum | journal = Eur. J. Biochem. | volume = 271 | pages = 4798–803 | pmid = 15606767 | doi = 10.1111/j.1432-1033.2004.04445.x | issue = 23–24 }}

{{isomerase-stub}}

[[Category:EC 5.1.1]]
[[Category:Enzymes of known structure]]

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