View source for Trans-2,3-dihydro-3-hydroxyanthranilate isomerase

{{Infobox enzyme
| Name = 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase
| EC_number = 5.4.4.6
| CAS_number = 
| IUBMB_EC_number = 5/4/4/6
| GO_code = 
| image = 
| width = 
| caption =
}}
'''9,12-octadecadienoate 8-hydroperoxide 8S-isomerase''' ({{EC number|5.4.4.6}}, ''8-hydroperoxide isomerase'', ''(8R,9Z,12Z)-8-hydroperoxy-9,12-octadecadienoate mutase ((7S,8S,9Z,12Z)-7,8-dihydroxy-9,12-octadecadienoate-forming)'') is an [[enzyme]] with system name ''(8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate hydroxymutase ((7S,8S,9Z,12Z)-7,8-dihydroxyoctadeca-9,12-dienoate-forming)''.<ref>{{cite journal | title = Sequential oxygenation of linoleic acid in the fungus <em>Gaeumannomyces graminis</em>: stereochemistry of dioxygenase and hydroperoxide isomerase reactions |author = Hamberg, M., Zhang, L.-Y., Brodowsky, I.D. and Oliw, E.H. |journal = Arch. Biochem. Biophys. |year = 1994 |volume = 309 |pages = 77–80 |pmid = 8117115 |doi=10.1006/abbi.1994.1087}}</ref><ref>{{cite journal | title = A protein radical and ferryl intermediates are generated by linoleate diol synthase, a ferric hemeprotein with dioxygenase and hydroperoxide isomerase activities |author = Su, C., Sahlin, M. and Oliw, E.H. |journal = J. Biol. Chem. |year = 1998 |volume = 273 |pages = 20744–20751 |pmid = 9694817 |doi=10.1074/jbc.273.33.20744}}</ref><ref>{{cite journal | title = Purification and characterization of linoleate 8-dioxygenase from the fungus <em>Gaeumannomyces graminis</em> as a novel hemoprotein |author = Su, C. and Oliw, E.H. |journal = J. Biol. Chem. |year = 1996 |volume = 271 |pages = 14112–14118 |pmid = 8662736 |doi=10.1074/jbc.271.24.14112}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate <math>\rightleftharpoons</math> (7S,8S,9Z,12Z)-7,8-dihydroxyoctadeca-9,12-dienoate

This enzyme contains [[heme]].

== References ==
{{reflist}}

== External links ==
* {{MeshName|9,12-octadecadienoate+8-hydroperoxide+8S-isomerase}}

[[Category:EC 5.4.4]]