View source for Phosphoglycerol geranylgeranyltransferase

{{enzyme
| Name = trans-pentaprenyltranstransferase
| EC_number = 2.5.1.33
| CAS_number = 83745-07-7
| IUBMB_EC_number = 2/5/1/33
| GO_code = 0048045
| image = 
| width = 
| caption = 
}}
In [[enzymology]], a '''trans-pentaprenyltranstransferase''' ({{EC number|2.5.1.33}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:all-trans-pentaprenyl diphosphate + isopentenyl diphosphate <math>\rightleftharpoons</math> diphosphate + all-trans-hexaprenyl diphosphate

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[all-trans-pentaprenyl diphosphate]] and [[isopentenyl diphosphate]], whereas its two [[product (chemistry)|products]] are [[diphosphate]] and [[all-trans-hexaprenyl diphosphate]].

This enzyme belongs to the family of [[transferase]]s, specifically those transferring aryl or alkyl groups other than methyl groups.  The systematic name of this enzyme class is '''all-trans-pentaprenyl-diphosphate:isopentenyl-diphosphate pentaprenyltranstransferase'''. Other names in common use include '''all-trans-hexaprenyl-diphosphate synthase''', '''hexaprenyl diphosphate synthase''', and '''hexaprenyl pyrophosphate synthetase'''.  This enzyme participates in [[biosynthesis of steroids]].  

==References==
{{reflist|1}}
* {{cite journal | author = Fujii H, Koyama T, Ogura K | date = 1982 | title = Hexaprenyl pyrophosphate synthetase from Micrococcus luteus B-P 26 Separation of two essential components | journal = J. Biol. Chem.  | volume = 257 | pages = 14610&ndash;2  | pmid = 7174655 | issue = 24 }}

{{transferase-stub}}

[[Category:EC 2.5.1]]
[[Category:Enzymes of unknown structure]]