View source for Exo-(1-4)-α-D-glucan lyase

{{Infobox enzyme
| Name = Alpha-bisabolene synthase
| EC_number = 4.2.3.38
| CAS_number = 
| IUBMB_EC_number = 4/2/3/38
| GO_code = 
| image = 
| width = 
| caption =
}}
'''Alpha-bisabolene synthase''' ({{EC number|4.2.3.38}}, ''bisabolene synthase'') is an [[enzyme]] with system name ''(2E,6E)-farnesyl-diphosphate diphosphate-lyase ((E)-alpha-bisabolene-forming)''.<ref>{{cite journal | title = Terpenoid-based defenses in conifers: cDNA cloning, characterization, and functional expression of wound-inducible (<em>E</em>)-&alpha;-bisabolene synthase  from grand fir (<em>Abies grandis</em>) |author = Bohlmann, J., Crock, J., Jetter, R. and Croteau, R. |journal = Proc. Natl. Acad. Sci. USA |year = 1998 |volume = 95 |pages = 6756–6761 |pmid = 9618485 |doi=10.1073/pnas.95.12.6756 |pmc=22624}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: (2E,6E)-farnesyl diphosphate <math>\rightleftharpoons</math> (E)-alpha-bisabolene + [[diphosphate]]

This synthase requires a divalent cation cofactor (Mg<sup>2+</sup> or, to a lesser extent, Mn<sup>2+</sup>) to neutralize the negative charge of the diphosphate leaving group. 

== References ==
{{reflist}}

== External links ==
* {{MeshName|Alpha-bisabolene+synthase}}

[[Category:EC 4.2.3]]