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{{Infobox enzyme
| Name = UDP-N-acetylmuramoyl-L-alanyl-D-glutamate—D-lysine ligase
| EC_number = 6.3.2.37
| CAS_number = 
| IUBMB_EC_number = 6/3/2/37
| GO_code = 
| image = 
| width = 
| caption =
}}
'''UDP-N-acetylmuramoyl-L-alanyl-D-glutamate—D-lysine ligase''' ({{EC number|6.3.2.37}}, ''UDP-MurNAc-L-Ala-D-Glu:D-Lys ligase'', ''D-lysine-adding enzyme'') is an [[enzyme]] with system name ''UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:D-lysine alpha-ligase (ADP-forming)''.<ref>{{cite journal | title = The MurE synthetase from ''Thermotoga maritima'' is endowed with an unusual D-lysine adding activity |author = Boniface, A., Bouhss, A., Mengin-Lecreulx, D. and Blanot, D. |journal = J. Biol. Chem. |year = 2006 |volume = 281 |pages = 15680–15686 |pmid = 16595662 |doi=10.1074/jbc.M506311200}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + D-lysine <math>\rightleftharpoons</math> ADP + [[phosphate]] + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-D-lysine

The enzyme from ''[[Thermotoga maritima]]'' also performs the reaction of [[EC 6.3.2.7]].

== References ==
{{reflist}}

== External links ==
* {{MeshName|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate—D-lysine+ligase}}

{{DEFAULTSORT:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-D-lysine ligase}}
[[Category:EC 6.3.2]]